Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | CCR1 | P32246 | 3/20 | 0.44 |
| ▸ | CCR5 | P51681 | 3/20 | 0.44 |
| ▸ | CCR8 | P51685 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24300010 | 0.89 | LMNA (0.46) | LMNAMAPTKDM4ETDP1CCR1 | |
| SCHEMBL23370403 | 0.85 | LMNA (0.37) | LMNAMAPTKDM4ETDP1CCR1 | |
| SCHEMBL22837821 | 0.85 | LMNA (0.44) | LMNAMAPTKDM4ETDP1CCR1 | |
| SCHEMBL13342143 | 0.84 | LMNA (0.41) | LMNAMAPTKDM4ETDP1CCR1 | |
| SCHEMBL19020368 | 0.81 | LMNA (0.43) | LMNAMAPTKDM4ETDP1CCR1 | |
| SCHEMBL21841122 | 0.80 | CCR1 (0.38) | LMNAMAPTKDM4ETDP1CCR1 | |
| SCHEMBL21370989 | 0.79 | CCR1 (0.32) | LMNAMAPTKDM4ETDP1CCR1 | |
| SCHEMBL23347433 | 0.79 | BRD4 (0.35) | LMNAMAPTKDM4ETDP1CCR1 | |
| SCHEMBL19322289 | 0.78 | CCR1 (0.44) | LMNAKDM4ECCR1CCR5RAB9A | |
| SCHEMBL19831120 | 0.78 | TDP1 (0.36) | LMNAMAPTKDM4ETDP1CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10804473-B2 | Electron transport materials for electronic applications | LG CHEM, LTD. (KR) | 2020-10-13 | — | — | US | disclosed |
| US-20200054647-A1 | RUTHENIUM COMPLEXES FOR TREATING CANCER WHICH COMPRISES CANCER STEM CELLS | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2020-02-20 | — | — | US | disclosed |
| US-10457703-B2 | Bile acid derivatives as FXR/TGR5 agonists and methods of use thereof | ENANTA PHARMACEUTICALS, INC. (US) | 2019-10-29 | — | — | US | disclosed |
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |
| US-20190070317-A1 | IN-VIVO REACTIVE SPECIES IMAGING | CALIPER LIFE SCIENCES, INC. | 2019-03-07 | — | — | US | disclosed |
| EP-2011175-B1 | METHODS OF MANUFACTURING ELECTRIC DEVICES | CAMBRIDGE DISPLAY TECH LTD (GB) | 2019-02-20 | — | — | EP | disclosed |
| US-20180065095-A1 | LIGHT-DRIVEN ION-PUMPING MEMBRANE SYSTEMS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10457703-B2 | Bile acid derivatives as FXR/TGR5 agonists and methods of use thereof | GPBAR1, NR1H4, SLC10A1 | LMNA 4562/4885MAPT 1709/4885KDM4E 4511/4885 |
| US-10804473-B2 | Electron transport materials for electronic applications | CCNE2, ESR2, CCNL2 | LMNA 1038/4885MAPT 3198/4885KDM4E 3342/4885 |
| US-20200054647-A1 | RUTHENIUM COMPLEXES FOR TREATING CANCER WHICH COMPRISES CANCER STEM CELLS | MYC, MYCBP, MCL1 | LMNA 3613/4885MAPT 3019/4885KDM4E 2445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.