Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.54 |
| ▸ | MAOB | P27338 | 7/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5786398 | 0.82 | MAPK1 (0.64) | TSHRMAPK1KDM4EMTNR1AMTNR1B | |
| SCHEMBL10338498 | 0.82 | MAOB (0.56) | TSHRMAPK1KDM4EMTNR1AMTNR1B | |
| SCHEMBL19944724 | 0.80 | KDM4E (0.49) | TSHRMAPK1KDM4EMAOBCYP2C9 | |
| SCHEMBL19944241 | 0.79 | CYP2C9 (0.78) | TSHRMAPK1KDM4ECYP2C9APP | |
| SCHEMBL17171595 | 0.79 | LMNA (0.57) | TSHRMTNR1AMTNR1BCYP2C9LMNA | |
| SCHEMBL1496491 | 0.79 | TSHR (0.70) | TSHRMAPK1KDM4EMTNR1AMTNR1B | |
| SCHEMBL8683292 | 0.79 | TAAR1 (0.61) | TSHRMAPK1KDM4EMTNR1AMTNR1B | |
| SCHEMBL29847698 | 0.79 | TSHR (0.70) | TSHRMAPK1KDM4EMTNR1AMTNR1B | |
| SCHEMBL11272514 | 0.79 | MAPK1 (0.60) | TSHRMAPK1KDM4EMTNR1AMTNR1B | |
| SCHEMBL8683297 | 0.79 | TAAR1 (0.61) | TSHRMAPK1KDM4EMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018041132-A1 | MONOMER, POLYMER, PREPARATION METHOD THEREFOR AND USE THEREOF | 广东东阳光药业有限公司 | 2018-03-08 | — | — | WO | disclosed |