SCHEMBL1994444

SCHEMBL1994444

COC(=O)c1cc(F)c(F)c(F)c1F

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
SOS1 Q07889 1/20 0.42
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA7 P43166 2/20 0.42
CA9 Q16790 2/20 0.42
CA14 Q9ULX7 2/20 0.42
PDK2 Q15119 1/20 0.42
PDK4 Q16654 1/20 0.42
KDM4E B2RXH2 5/20 0.42
GAA P10253 3/20 0.42
LMNA P02545 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
POLB P06746 1/20 0.42
NFKB1 P19838 1/20 0.42
XDH P47989 1/20 0.42
GFER P55789 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6644948 0.86 KDM4E (0.47) MAPTTDP1CA12CA1CA2
SCHEMBL6647182 0.86 MAPT (0.40) MAPTTDP1SMN1; SMN2SOS1CA12
SCHEMBL8979022 0.86 KDM4E (0.47) TDP1SMN1; SMN2SOS1CA12CA1
SCHEMBL18149338 0.86 KDM4E (0.46) MAPTSOS1CA12CA1CA2
SCHEMBL522850 0.86 MAPT (0.44) MAPTTDP1SOS1CA12CA1
SCHEMBL2831221 0.84 KDM4E (0.45) TDP1SOS1CA12CA1CA2
SCHEMBL17700276 0.84 KDM4E (0.45) TDP1SOS1CA12CA1CA2
SCHEMBL7595029 0.84 SOS1 (0.49) MAPTTDP1SOS1CA12CA1
SCHEMBL18149676 0.84 SOS1 (0.45) MAPTTDP1SOS1CA12CA1
SCHEMBL7491095 0.84 SOS1 (0.45) MAPTTDP1SOS1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119613699-A Method for removing perfluoro polyether acyl fluoride end group 南开大学 2025-03-14 CN claimed
CN-115306376-A Oil-gas well fracturing monitoring reagent, method and application thereof 中国石油天然气股份有限公司 2022-11-08 CN claimed
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US claimed
CN-119613699-A Method for removing perfluoro polyether acyl fluoride end group 南开大学 2025-03-14 CN disclosed
CN-114478520-B Bcl-2 protein apoptosis inducer and application thereof 杭州和正医药有限公司 2025-01-10 CN disclosed
CN-118955560-A Light-induced polyfluoroaromatic hydrocarbon phosphonation process 南京师范大学 2024-11-15 CN disclosed
US-20230242705-A1 ESTER COMPOUND AND RESIN COMPOSITION AJINOMOTO CO., INC. (JP) 2023-08-03 US disclosed
US-20230203055-A1 FUSED RING COMPOUND AND APPLICATION THEREOF IN MEDICINE BETTA PHARMACEUTICALS CO., LTD (CN) 2023-06-29 US disclosed
CN-115306376-A Oil-gas well fracturing monitoring reagent, method and application thereof 中国石油天然气股份有限公司 2022-11-08 CN disclosed
US-20220298174-A1 TETRACYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF SHANGHAI JEMINCARE PHARMACEUTICALS CO., LTD (CN) 2022-09-22 US disclosed
EP-4011886-A1 TETRACYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF Shanghai Jemincare Pharmaceuticals Co., Ltd. (CN) 2022-06-15 EP disclosed
CN-102603531-A Method for preparing 2,3,4,5-tetrafluoro methyl benzoate in series reaction XIANJU LITIAN CHEMICAL CO LTD 2012-07-25 CN disclosed
CN-102603531-A Method for preparing 2,3,4,5-tetrafluoro methyl benzoate in series reaction XIANJU LITIAN CHEMICAL CO LTD 2012-07-25 CN disclosed
US-20110172336-A1 FLUOROCOPOLYMER COMPOSITION AND ITS PRODUCTION PROCESS ASAHI GLASS COMPANY, LIMITED (JP) 2011-07-14 US disclosed
EP-2338935-A1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS COMPANY, LIMITED (JP) 2011-06-29 EP disclosed
EP-0877011-A1 Processes for producing tetra-fluorophthalic anhydride and fluorobenzoic acids ASAHI GLASS COMPANY LTD. (JP) 1998-11-11 EP disclosed
EP-0866050-A1 Processes for producing tetra-fluorophthalic anhydride and fluorobenzioc acids ASAHI GLASS COMPANY LTD. (JP) 1998-09-23 EP disclosed
US-5648504-A MULTISTAGE PROCESS WITH CHLORINATION OF TETRACHLOROPHTHALIC ANHYDRIDE TO 3,3,4,5,6,7-HEXACHLORO-1-(3H)-ISOBENZOFURANONE THEN FLUORINATION AND REACTING WITH INORGANIC BASE OR ACID ASAHI GLASS COMPANY LTD. (JP) 1997-07-15 US disclosed
US-5523476-A Processes for producing tetrafluorophthalic anhydride and fluorobenzoic acids ASAHI GLASS COMPANY LTD. (JP) 1996-06-04 US disclosed
EP-0669310-A1 Processes for producing tetrafluorophtahlic anhydride and fluorobenzoic acids ASAHI GLASS COMPANY LTD. (JP) 1995-08-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230203055-A1 FUSED RING COMPOUND AND APPLICATION THEREOF IN MEDICINE VIP, CYP11B2, CYP11B1 MAPT 4055/4885TDP1 4192/4885SMN1; SMN2 4479/4885
US-20220298174-A1 TETRACYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF KRAS, NRAS, HRAS MAPT 3413/4885TDP1 3750/4885SMN1; SMN2 4358/4885
US-20230242705-A1 ESTER COMPOUND AND RESIN COMPOSITION AFF4, AFF1, AFF2 MAPT 2274/4885TDP1 3118/4885SMN1; SMN2 2963/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.