Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 13/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1992679 | 0.81 | MEN1 (0.43) | TSHRS1PR2 | |
| SCHEMBL12563577 | 0.72 | MCHR1 (0.46) | PTGDR2 | |
| SCHEMBL29937094 | 0.71 | MAPT (0.40) | S1PR2 | |
| SCHEMBL1992185 | 0.71 | MAPT (0.40) | S1PR2 | |
| SCHEMBL27822168 | 0.70 | AKR1B1 (0.51) | TSHRPTGDR2AKR1B1 | |
| SCHEMBL27587093 | 0.68 | AKR1B1 (0.38) | PTGDR2AKR1B1S1PR2AGBL2 | |
| SCHEMBL18455649 | 0.68 | MAPT (0.41) | — | |
| SCHEMBL23640325 | 0.68 | MAPT (0.49) | TSHRPTGDR2AKR1B1AGBL2 | |
| SCHEMBL9512394 | 0.68 | MAPT (0.68) | TSHRAKR1B1AGBL2 | |
| SCHEMBL2172584 | 0.68 | PTGDR2 (0.46) | TSHRPTGDR2AKR1C3AKR1C2AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011079105-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-30 | — | — | WO | disclosed |
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | TPMT, TSLP, THPO | TSHR 752/4885PTGDR2 61/4885AKR1C3 593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.