Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 11/20 | 0.41 |
| ▸ | RIPK3 | Q9Y572 | 8/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1996343 | 0.80 | MAPK14 (0.43) | MAPK14RIPK3SRCBRAFKDR | |
| SCHEMBL1995955 | 0.77 | MAPK14 (0.43) | MAPK14RIPK3SRCBRAFKDR | |
| SCHEMBL1997890 | 0.77 | MAPK14 (0.55) | MAPK14RIPK3 | |
| SCHEMBL1995963 | 0.72 | MAPK14 (0.52) | MAPK14RIPK3 | |
| SCHEMBL1995055 | 0.72 | RIPK3 (0.58) | MAPK14RIPK3 | |
| SCHEMBL1998934 | 0.71 | MAPK14 (0.48) | MAPK14RIPK3 | |
| SCHEMBL2001207 | 0.71 | QPCT (0.48) | MAPK14RIPK3 | |
| SCHEMBL1994116 | 0.70 | MAPK14 (0.70) | MAPK14RIPK3 | |
| SCHEMBL1996441 | 0.70 | MAPK14 (0.54) | MAPK14RIPK3 | |
| SCHEMBL1993317 | 0.69 | MAPK14 (0.67) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2338890-A1 | 4,7-Diazaindole derivatives and their use as fungicides | Bayer CropScience AG (DE) | 2011-06-29 | — | — | EP | claimed |
| EP-2338890-A1 | 4,7-Diazaindole derivatives and their use as fungicides | Bayer CropScience AG (DE) | 2011-06-29 | — | — | EP | disclosed |