SCHEMBL1994596

SCHEMBL1994596

CCCOC(=O)c1ccc(C(=O)Br)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.70
TSHR P16473 3/20 0.70
ESR1 P03372 3/20 0.70
TDP1 Q9NUW8 2/20 0.70
CHRM1 P11229 1/20 0.70
SLC6A2 P23975 1/20 0.70
KDR P35968 1/20 0.70
LMNA P02545 4/20 0.67
STS P08842 1/20 0.57
SMN1; SMN2 Q16637 3/20 0.56
CYP1A2 P05177 2/20 0.56
CYP2C19 P33261 2/20 0.56
MAPK1 P28482 2/20 0.56
CYP2D6 P10635 1/20 0.56
NR1H2 P55055 1/20 0.56
RNASEL Q05823 1/20 0.56
HPGD P15428 3/20 0.55
MAPT P10636 5/20 0.55
KMT2A Q03164 2/20 0.55
CYP3A4 P08684 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL49950 0.90 ALDH1A1 (0.84) ALDH1A1TSHRESR1TDP1CHRM1
SCHEMBL1994616 0.89 ESR1 (0.72) ALDH1A1TSHRESR1TDP1CHRM1
SCHEMBL27647510 0.88 ALDH1A1 (0.81) ALDH1A1TSHRESR1TDP1CHRM1
SCHEMBL27647586 0.88 ALDH1A1 (0.81) ALDH1A1TSHRESR1TDP1CHRM1
SCHEMBL27647504 0.88 ALDH1A1 (0.81) ALDH1A1TSHRESR1TDP1CHRM1
Methane SCHEMBL27699232 0.88 ALDH1A1 (0.81) ALDH1A1TSHRESR1TDP1CHRM1
SCHEMBL28758641 0.88 ALDH1A1 (0.81) ALDH1A1TSHRESR1TDP1CHRM1
SCHEMBL27667930 0.88 ALDH1A1 (0.81) ALDH1A1TSHRESR1TDP1CHRM1
SCHEMBL27667922 0.88 ALDH1A1 (0.81) ALDH1A1TSHRESR1TDP1CHRM1
SCHEMBL27647501 0.88 ALDH1A1 (0.81) ALDH1A1TSHRESR1TDP1CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8773745-B2 Electrochromic material KYUSHU UNIVERSITY (JP) 2014-07-08 US disclosed
US-20110149367-A1 ELECTROCHROMIC MATERIAL KYUSHU UNIVERSITY (JP) 2011-06-23 US disclosed