Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15562155 | 0.93 | AAK1 (0.52) | AAK1ROCK2 | |
| SCHEMBL19946030 | 0.88 | AAK1 (0.62) | AAK1ROCK2 | |
| SCHEMBL19946124 | 0.85 | AAK1 (0.65) | AAK1 | |
| SCHEMBL19946177 | 0.85 | AAK1 (0.71) | AAK1ROCK2 | |
| SCHEMBL16972637 | 0.83 | AAK1 (0.47) | AAK1 | |
| SCHEMBL15562077 | 0.79 | AAK1 (0.51) | AAK1ROCK2 | |
| SCHEMBL15455689 | 0.78 | AAK1 (0.61) | AAK1ROCK2 | |
| SCHEMBL20176303 | 0.77 | AAK1 (0.75) | AAK1 | |
| SCHEMBL15562104 | 0.77 | AAK1 (0.55) | AAK1ROCK2 | |
| SCHEMBL15562193 | 0.77 | AAK1 (0.50) | AAK1ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3292124-A2 | FUSED PYRIDINES AS ADAPTOR ASSOCIATED KINASE 1 (AAK1) INHIBITORS | Bristol-Myers Squibb Company (US) | 2018-03-14 | — | — | EP | disclosed |