Biphenyl

Biphenyl

SCHEMBL1994657

c1ccc(-c2ccccc2)cc1.c1ccc(-c2ccccc2-c2ccccc2)cc1

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.69
HSD17B10 Q99714 3/20 0.58
BCL2L1 Q07817 2/20 0.58
MAPK1 P28482 2/20 0.58
HPGD P15428 1/20 0.58
CYP2A6 P11509 1/20 0.58
BACE1 P56817 1/20 0.53
DPP4 P27487 1/20 0.50
PTGS2 P35354 1/20 0.50
HDAC4 P56524 1/20 0.48
HDAC2 Q92769 1/20 0.48
HDAC8 Q9BY41 1/20 0.48
HDAC6 Q9UBN7 1/20 0.48
TDP1 Q9NUW8 2/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
TAAR1 Q96RJ0 1/20 0.47
NOTUM Q6P988 1/20 0.47
MMP3 P08254 1/20 0.47
GPR55 Q9Y2T6 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30257106 0.96 ALDH1A1 (0.64) ALDH1A1HSD17B10BCL2L1MAPK1HPGD
SCHEMBL30516212 0.96 ALDH1A1 (0.64) ALDH1A1HSD17B10BCL2L1MAPK1HPGD
SCHEMBL5951150 0.96 ALDH1A1 (0.64) ALDH1A1HSD17B10BCL2L1MAPK1HPGD
Tannin Pyrogallol SCHEMBL13685561 0.96 ALDH1A1 (0.64) ALDH1A1HSD17B10BCL2L1MAPK1HPGD
SCHEMBL21447 0.96 ALDH1A1 (0.61) ALDH1A1HSD17B10BCL2L1MAPK1HPGD
SCHEMBL2361430 0.96 ALDH1A1 (0.61) ALDH1A1HSD17B10BCL2L1MAPK1HPGD
Benzene SCHEMBL28035419 0.96 ALDH1A1 (0.61) ALDH1A1HSD17B10BCL2L1MAPK1HPGD
SCHEMBL28184105 0.93 ALDH1A1 (0.60) ALDH1A1HSD17B10BCL2L1MAPK1HPGD
SCHEMBL13387362 0.92 ALDH1A1 (0.58) ALDH1A1HSD17B10BCL2L1MAPK1HPGD
Water SCHEMBL9138909 0.92 ALDH1A1 (0.58) ALDH1A1HSD17B10BCL2L1MAPK1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9010318-B2 Extended-range heat transfer fluid using variable composition WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2015-04-21 US claimed
US-20110146959-A1 EXTENDED-RANGE HEAT TRANSFER FLUID USING VARIABLE COMPOSITION WISCONSIN ALUMNI RESEARCH FOUNDATION 2011-06-23 US claimed
US-9010318-B2 Extended-range heat transfer fluid using variable composition WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2015-04-21 US disclosed
US-20110146959-A1 EXTENDED-RANGE HEAT TRANSFER FLUID USING VARIABLE COMPOSITION WISCONSIN ALUMNI RESEARCH FOUNDATION 2011-06-23 US disclosed
US-4596663-A Carboxylic acylating agents substituted with olefin polymers of high molecular weight mono-olefins, derivatives thereof, and fuels and lubricants containing same THE LUBRIZOL CORPORATION (US) 1986-06-24 US disclosed
US-4022717-A HYDROGEN FLUORIDE, OXYGEN E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-05-10 US disclosed