SCHEMBL1994730

SCHEMBL1994730

CCCCCCCCCCC(CCCCCCCC)CC(CCCCCCCC)C(=O)O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 3/20 0.68
GRIK2 Q13002 3/20 0.68
SLC1A2 P43004 3/20 0.65
SLC1A1 P43005 3/20 0.65
SLC1A3 P43003 2/20 0.56
CA2 P00918 2/20 0.55
MAPK1 P28482 1/20 0.55
GPR84 Q9NQS5 5/20 0.53
FFAR1 O14842 1/20 0.53
MAPT P10636 1/20 0.52
LCK P06239 1/20 0.52
PPARD Q03181 1/20 0.52
ZDHHC20 Q5W0Z9 1/20 0.52
ZDHHC2 Q9UIJ5 1/20 0.52
ACE2 Q9BYF1 1/20 0.48
LMNA P02545 1/20 0.48
CHRM1 P11229 1/20 0.46
AKR1A1 P14550 1/20 0.46
CHRM3 P20309 1/20 0.46
HTR2A P28223 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4953873 1.00 GRIK1 (0.68) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL61968 1.00 GRIK1 (0.68) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL20767329 1.00 GRIK1 (0.68) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL20767325 1.00 GRIK1 (0.68) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL20767293 1.00 GRIK1 (0.68) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL20767278 1.00 GRIK1 (0.68) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL21248005 1.00 GRIK1 (0.68) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL20767409 1.00 GRIK1 (0.68) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL20767301 1.00 GRIK1 (0.68) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL4429724 1.00 GRIK1 (0.68) GRIK1GRIK2SLC1A2SLC1A1SLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9309481-B2 Lubricant composition IDEMITSU KOSAN CO., LTD. (JP) 2016-04-12 US disclosed
US-9074158-B2 Detergent-dispersant, additive composition for lubricant, and lubricant composition IDEMITSU KOSAN CO., LTD. (JP) 2015-07-07 US disclosed
CN-103215107-B Detergent dispersant, additive composition for lubricating oil, and lubricating oil composition IDEMITSU KOSAN CO 2015-03-11 CN disclosed
US-8853139-B2 Detergent-dispersant, additive composition for lubricant, and lubricant composition IDEMITSU KOSAN CO., LTD. (JP) 2014-10-07 US disclosed
US-20140296115-A1 DETERGENT-DISPERSANT, ADDITIVE COMPOSITION FOR LUBRICANT, AND LUBRICANT COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2014-10-02 US disclosed
US-8841242-B2 Anti-wear agent, additive composition for lubricant, and lubricant composition IDEMITSU KOSAN CO., LTD. (JP) 2014-09-23 US disclosed
CN-103215107-A Detergent dispersant, additive composition for lubricating oil, and lubricating oil composition IDEMITSU KOSAN CO 2013-07-24 CN disclosed
US-20130045904-A1 DETERGENT-DISPERSANT, ADDITIVE COMPOSITION FOR LUBRICANT, AND LUBRICANT COMPOSITION IWASAKI JUNYA (JP) 2013-02-21 US disclosed
EP-2546324-A1 LUBRICANT COMPOSITION Idemitsu Kosan Co., Ltd. (JP) 2013-01-16 EP disclosed
US-20130005624-A1 LUBRICANT COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2013-01-03 US disclosed
EP-2520638-A1 Anti-wear agent, additive composition for lubricant, and lubricant composition IDEMITSU KOSAN CO., LTD. (JP) 2012-11-07 EP disclosed
US-20110152145-A1 ANTI-WEAR AGENT, ADDITIVE COMPOSITION FOR LUBRICANT, AND LUBRICANT COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2011-06-23 US disclosed
US-20100184982-A1 DETERGENT-DISPERSANT, ADDITIVE COMPOSITION FOR LUBRICANT, AND LUBRICANT COMPOSITION IDEMITSU KOSAN CO., LTD (JP) 2010-07-22 US disclosed
EP-2177594-A1 ANTI-WEAR AGENT, ADDITIVE COMPOSITION FOR LUBRICANT, AND LUBRICANT COMPOSITION Idemitsu Kosan Co., Ltd. (JP) 2010-04-21 EP disclosed
CN-101679898-A Detergent dispersant, additive composition for lubricant, and lubricating oil composition IDEMITSU KOSAN CO 2010-03-24 CN disclosed
EP-2161324-A1 DETERGENT-DISPERSANT, ADDITIVE COMPOSITION FOR LUBRICANT, AND LUBRICANT COMPOSITION Idemitsu Kosan Co., Ltd. (JP) 2010-03-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100184982-A1 DETERGENT-DISPERSANT, ADDITIVE COMPOSITION FOR LUBRICANT, AND LUBRICANT COMPOSITION DSC1, DSP, CDC73 GRIK1 1324/4885GRIK2 2112/4885SLC1A2 4853/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.