SCHEMBL1994943

SCHEMBL1994943

CCCO[SiH](CCOCC1CO1)OCCC

nearest known ligand 0.56

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.56
ALDH1A1 P00352 5/20 0.53
TDP1 Q9NUW8 1/20 0.53
TSHR P16473 2/20 0.48
MAPK1 P28482 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9181851 0.90 SMN1; SMN2 (0.68) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL153463 0.90 SMN1; SMN2 (0.62) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL230764 0.88 ALDH1A1 (0.62) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL229582 0.87 SMN1; SMN2 (0.53) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL9804693 0.87 ALDH1A1 (0.65) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL9804542 0.85 ALDH1A1 (0.63) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL15378124 0.84 SMN1; SMN2 (0.65) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL4273639 0.84 SMN1; SMN2 (0.53) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL2551786 0.81 SMN1; SMN2 (0.71) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL143771 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5158289-A Head covered with a cured coating layer of a silicone-modified synthetic resin THE YOKOHAMA RUBBER CO., LTD. (JP) 1992-10-27 US claimed
EP-2803699-B1 RUBBER COMPOSITION FOR TIRE, VULCANIZED RUBBER COMPOSITION FOR TIRE, AND TIRES USING SAME BRIDGESTONE CORP (JP) 2018-09-12 EP disclosed
US-9623705-B2 Method for producing modified conjugated diene polymer/copolymer, modified conjugated diene polymer/copolymer, and rubber composition and tire using the same BRIDGESTONE CORPORATION (JP) 2017-04-18 US disclosed
US-9447208-B2 Rubber composition for tire, vulcanized rubber composition for tire, and tires using same BRIDGESTONE CORPORATION (JP) 2016-09-20 US disclosed
US-20140357804-A1 RUBBER COMPOSITION FOR TIRE, VULCANIZED RUBBER COMPOSITION FOR TIRE, AND TIRES USING SAME BRIDGESTONE CORPORATION (JP) 2014-12-04 US disclosed
EP-2803699-A1 RUBBER COMPOSITION FOR TIRE, VULCANIZED RUBBER COMPOSITION FOR TIRE, AND TIRES USING SAME Bridgestone Corporation (JP) 2014-11-19 EP disclosed
EP-2266819-B1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, AND RUBBER COMPOSITION AND TIER USING THE SAME BRIDGESTONE CORP (JP) 2013-11-06 EP disclosed
US-20110146877-A1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, AND RUBBER COMPOSITION AND TIER USING THE SAME BRIDGESTONE CORPORATION (JP) 2011-06-23 US disclosed
EP-2266819-A1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, AND RUBBER COMPOSITION AND TIER USING THE SAME Bridgestone Corporation (JP) 2010-12-29 EP disclosed
EP-0526975-B1 Coating composition for optical plastic moldings ITOH OPTICAL IND (JP) 1995-07-26 EP disclosed
US-5322888-A Curable mixture of hydrolyzable silicate, epoxy-containing silane, dicarboxylic acid or anhydride, and imidazole catalyst; protective coating for optical substrate having a high refractive index; radiation resistance ITOH OPTICAL INDUSTRIAL CO., LTD. (JP) 1994-06-21 US disclosed
EP-0526975-A2 Coating composition for optical plastic moldings ITOH OPTICAL INDUSTRIAL CO., LTD. (JP) 1993-02-10 EP disclosed