⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30828786 | 1.00 | — | — | |
| SCHEMBL245466 | 1.00 | — | — | |
| SCHEMBL4146707 | 1.00 | — | — | |
| SCHEMBL417278 | 1.00 | — | — | |
| SCHEMBL13645939 | 1.00 | — | — | |
| SCHEMBL25527642 | 1.00 | — | — | |
| SCHEMBL7771659 | 1.00 | — | — | |
| Ammonia Solution, Strong SCHEMBL25431321 | 0.97 | — | — | |
| Iodide SCHEMBL4974469 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL2018586 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365594-A1 | THIENOPYRROLE COMPOUNDS | GILEAD SCIENCES, INC. | 2023-11-16 | — | — | US | disclosed |
| US-11661431-B2 | Thienopyrrole compounds | GILEAD SCIENCES, INC. (US) | 2023-05-30 | — | — | US | disclosed |
| US-10696663-B2 | Chromene derivatives as inhibitors of TCR-NCK interaction | ARTAX BIOPHARMA INC. (US) | 2020-06-30 | — | — | US | disclosed |
| US-20190263792-A1 | CHROMENE DERIVATIVES AS INHIBITORS OF TCR-NCK INTERACTION | ARTAX BIOPHARMA INC. | 2019-08-29 | — | — | US | disclosed |
| EP-3510032-A1 | PYRAZOLOPYRIDINE DERIVATIVES AS HPK1 MODULATORS AND USES THEREOF FOR THE TREATMENT OF CANCER | Incyte Corporation (US) | 2019-07-17 | — | — | EP | disclosed |
| WO-2018049200-A1 | PYRAZOLOPYRIDINE DERIVATIVES AS HPK1 MODULATORS AND USES THEREOF FOR THE TREATMENT OF CANCER | INCYTE CORPORATION (US) | 2018-03-15 | — | — | WO | disclosed |