⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19951622 | 1.00 | — | — | |
| SCHEMBL30828786 | 1.00 | — | — | |
| SCHEMBL245466 | 1.00 | — | — | |
| SCHEMBL417278 | 1.00 | — | — | |
| SCHEMBL13645939 | 1.00 | — | — | |
| SCHEMBL25527642 | 1.00 | — | — | |
| SCHEMBL7771659 | 1.00 | — | — | |
| Ammonia Solution, Strong SCHEMBL25431321 | 0.97 | — | — | |
| Iodide SCHEMBL4974469 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL2018586 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019035008-A1 | CDK4/6 INHIBITORS AND USE THEREOF | BEIJING XUANYI PHARMASCIENCES CO., LTD. (CN) | 2019-02-21 | — | — | WO | disclosed |
| US-20140329784-A1 | 2-PHENYL-1-[4-(2-AMINOETHOXY)-BENZYL]-INDOLE AND ESTROGEN FORMULATIONS | WYETH LLC (US) | 2014-11-06 | — | — | US | disclosed |
| US-8815934-B2 | 2-Phenyl-1-[4-(2-Aminoethoxy)-Benzyl]-Indole and estrogen formulations | WYETH LLC (US) | 2014-08-26 | — | — | US | disclosed |
| US-20120252769-A1 | 2-PHENYL-1-[4-(2-AMINOETHOXY)-BENZYL]-INDOLE AND ESTROGEN FORMULATIONS | WYETH LLC (US) | 2012-10-04 | — | — | US | disclosed |
| US-20090176764-A1 | 2-PHENYL-1-[4-(2-AMINOETHOXY)-BENZYL]-INDOLES AS ESTROGENIC AGENTS | WYETH (US) | 2009-07-09 | — | — | US | disclosed |
| EP-1968980-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES, LTD. (IN) | 2008-09-17 | — | — | EP | disclosed |
| US-20080021017-A1 | 2-Phenyl-1-[4-(2-aminoethoxy)-benzyl]-indoles as estrogenic agents | WYETH (US) | 2008-01-24 | — | — | US | disclosed |
| WO-2007110782-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-10-04 | — | — | WO | disclosed |
| US-7247624-B2 | 2-Phenyl-1-[4-(2-aminoethoxy)-benzyl]-indoles as estrogenic agents | WYETH (US) | 2007-07-24 | — | — | US | disclosed |
| US-20070142361-A1 | 2-Phenyl-1-[4-(2-aminoethoxy)-benzyl]-indole and estrogen formulations | WYETH (US) | 2007-06-21 | — | — | US | disclosed |
| US-20040110823-A1 | 2-Phenyl-1-[4-(2-aminoethoxy)-benzyl]-indoles as estrogenic agents | WYETH | 2004-06-10 | — | — | US | disclosed |
| US-20030203883-A1 | For alleviating symptoms of post-menopausal syndrome; hormone replacement therapy; for treating endometriosis | WYETH | 2003-10-30 | — | — | US | disclosed |
| US-20030130274-A1 | 2-Phenyl-1-[4-(2-aminoethoxy)benzyl-indoles as estrogenic agents | WYETH | 2003-07-10 | — | — | US | disclosed |
| CN-1397549-A | Novel derivative of 2-azadicyclo-(2,2,1) heptane, its prepn. and use | AVENTIS PHARMA (FR) | 2003-02-19 | — | — | CN | disclosed |
| US-6326367-B1 | THERAPY FOR OVARIAN CANCER | AMERICAN HOME PRODUCTS CORPORATION | 2001-12-04 | — | — | US | disclosed |
| US-6291451-B1 | USEFUL IN THE TREATMENT OR INHIBITION OF BREAST CANCER. | AMERICAN HOME PRODUCTS CORPORATION | 2001-09-18 | — | — | US | disclosed |
| US-6225308-B1 | 2-PHENYL-1-(4-(2-AMINOETHOXY)-BENZYL)-INDOLE COMPOUNDS WHICH ARE USEFUL AS ESTROGENIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION | 2001-05-01 | — | — | US | disclosed |
| US-6127404-A | 2-PHENYL-1-(4-(2-AMINOETHOXY)-BENZYL)INDOLE COMPOUNDS USEFUL AS ESTROGEN AGONISTS/ANTAGONISTS; OSTEOPOROSIS; ANTICHOLESTEROL AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-10-03 | — | — | US | disclosed |
| US-5631383-A | Derivatives of 2-azabicyclo[2.2.1]heptane, their preparation and their application | RHONE-POULENC RORER S.A. (FR) | 1997-05-20 | — | — | US | disclosed |
| US-5631383-A | Derivatives of 2-azabicyclo[2.2.1]heptane, their preparation and their application | RHONE-POULENC RORER S.A. (FR) | 1997-05-20 | — | — | US | disclosed |