SCHEMBL1995168

SCHEMBL1995168

O=C(O)[C@H](C[C@H](F)C(=O)O)CP(=O)(O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 11/20 1.00
NAALAD2 Q9Y3Q0 1/20 0.52
ANPEP P15144 1/20 0.41
LAP3 P28838 1/20 0.41
GABBR2 O75899 1/20 0.40
GABBR1 Q9UBS5 1/20 0.40
GRM3 Q14832 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1998330 1.00 FOLH1 (1.00) FOLH1NAALAD2ANPEPLAP3GABBR2
SCHEMBL1997642 1.00 FOLH1 (1.00) FOLH1NAALAD2ANPEPLAP3GABBR2
SCHEMBL14330735 1.00 FOLH1 (1.00) FOLH1NAALAD2ANPEPLAP3GABBR2
SCHEMBL14330756 1.00 FOLH1 (1.00) FOLH1NAALAD2ANPEPLAP3GABBR2
SCHEMBL2032825 1.00 FOLH1 (1.00) FOLH1NAALAD2ANPEPLAP3GABBR2
SCHEMBL14330734 1.00 FOLH1 (1.00) FOLH1NAALAD2ANPEPLAP3GABBR2
SCHEMBL2001657 1.00 FOLH1 (1.00) FOLH1NAALAD2ANPEPLAP3GABBR2
SCHEMBL14330757 1.00 FOLH1 (1.00) FOLH1NAALAD2ANPEPLAP3GABBR2
SCHEMBL2031866 1.00 FOLH1 (1.00) FOLH1NAALAD2ANPEPLAP3GABBR2
SCHEMBL14330758 1.00 FOLH1 (1.00) FOLH1NAALAD2ANPEPLAP3GABBR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110730908-B Engineered cells expressing Prostate Specific Membrane Antigen (PSMA) or modified versions thereof and related methods 朱诺治疗学股份有限公司 2025-01-21 CN claimed
CN-110730908-A Engineered cells expressing Prostate Specific Membrane Antigen (PSMA) or modified forms thereof and related methods 朱诺治疗学股份有限公司 2020-01-24 CN claimed
US-20120328518-A1 PROSTATE SPECIFIC MEMBRANE ANTIGEN INHIBITORS PIRAMAL IMAGING SA (CH) 2012-12-27 US claimed
EP-2513121-A1 PROSTATE SPECIFIC MEMBRANE ANTIGEN INHIBITORS Piramal Imaging SA (CH) 2012-10-24 EP claimed
EP-2338892-A1 Prostate specific membrane antigen inhibitors Bayer Schering Pharma Aktiengesellschaft (DE) 2011-06-29 EP claimed
WO-2011073286-A1 PROSTATE SPECIFIC MEMBRANE ANTIGEN INHIBITORS BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2011-06-23 WO claimed
CN-110730908-B Engineered cells expressing Prostate Specific Membrane Antigen (PSMA) or modified versions thereof and related methods 朱诺治疗学股份有限公司 2025-01-21 CN disclosed
CN-110730908-A Engineered cells expressing Prostate Specific Membrane Antigen (PSMA) or modified forms thereof and related methods 朱诺治疗学股份有限公司 2020-01-24 CN disclosed
US-20120328518-A1 PROSTATE SPECIFIC MEMBRANE ANTIGEN INHIBITORS PIRAMAL IMAGING SA (CH) 2012-12-27 US disclosed
US-20120328518-A1 PROSTATE SPECIFIC MEMBRANE ANTIGEN INHIBITORS PIRAMAL IMAGING SA (CH) 2012-12-27 US disclosed
US-20120328518-A1 PROSTATE SPECIFIC MEMBRANE ANTIGEN INHIBITORS PIRAMAL IMAGING SA (CH) 2012-12-27 US disclosed
EP-2513121-A1 PROSTATE SPECIFIC MEMBRANE ANTIGEN INHIBITORS Piramal Imaging SA (CH) 2012-10-24 EP disclosed
EP-2338892-A1 Prostate specific membrane antigen inhibitors Bayer Schering Pharma Aktiengesellschaft (DE) 2011-06-29 EP disclosed
EP-2338892-A1 Prostate specific membrane antigen inhibitors Bayer Schering Pharma Aktiengesellschaft (DE) 2011-06-29 EP disclosed
WO-2011073286-A1 PROSTATE SPECIFIC MEMBRANE ANTIGEN INHIBITORS BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2011-06-23 WO disclosed
WO-2011073286-A1 PROSTATE SPECIFIC MEMBRANE ANTIGEN INHIBITORS BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2011-06-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120328518-A1 PROSTATE SPECIFIC MEMBRANE ANTIGEN INHIBITORS KLK3, FOLH1, ACP3 FOLH1 2/4885NAALAD2 123/4885ANPEP 119/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.