SCHEMBL2032825

SCHEMBL2032825

O=C(O)C(F)C[C@@H](CP(=O)(O)O)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 11/20 1.00
NAALAD2 Q9Y3Q0 1/20 0.52
ANPEP P15144 1/20 0.41
LAP3 P28838 1/20 0.41
GABBR2 O75899 1/20 0.40
GABBR1 Q9UBS5 1/20 0.40
GRM3 Q14832 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1998330 1.00 FOLH1 (1.00) FOLH1NAALAD2ANPEPLAP3GABBR2
SCHEMBL1997642 1.00 FOLH1 (1.00) FOLH1NAALAD2ANPEPLAP3GABBR2
SCHEMBL14330735 1.00 FOLH1 (1.00) FOLH1NAALAD2ANPEPLAP3GABBR2
SCHEMBL14330756 1.00 FOLH1 (1.00) FOLH1NAALAD2ANPEPLAP3GABBR2
SCHEMBL14330734 1.00 FOLH1 (1.00) FOLH1NAALAD2ANPEPLAP3GABBR2
SCHEMBL2001657 1.00 FOLH1 (1.00) FOLH1NAALAD2ANPEPLAP3GABBR2
SCHEMBL14330757 1.00 FOLH1 (1.00) FOLH1NAALAD2ANPEPLAP3GABBR2
SCHEMBL2031866 1.00 FOLH1 (1.00) FOLH1NAALAD2ANPEPLAP3GABBR2
SCHEMBL1995168 1.00 FOLH1 (1.00) FOLH1NAALAD2ANPEPLAP3GABBR2
SCHEMBL14330758 1.00 FOLH1 (1.00) FOLH1NAALAD2ANPEPLAP3GABBR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2513121-A1 PROSTATE SPECIFIC MEMBRANE ANTIGEN INHIBITORS Piramal Imaging SA (CH) 2012-10-24 EP disclosed
EP-2338892-A1 Prostate specific membrane antigen inhibitors Bayer Schering Pharma Aktiengesellschaft (DE) 2011-06-29 EP disclosed
WO-2011073286-A1 PROSTATE SPECIFIC MEMBRANE ANTIGEN INHIBITORS BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2011-06-23 WO disclosed