Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4778401 | 0.78 | CYP1A2 (0.46) | ALDH1A1GLAHPGDKDM4EGAA | |
| SCHEMBL467131 | 0.74 | KDM4E (0.37) | ALDH1A1GLAHPGDKDM4EGAA | |
| SCHEMBL183634 | 0.73 | KDM4E (0.33) | ALDH1A1GLAHPGDKDM4EGAA | |
| SCHEMBL1385432 | 0.73 | ALDH1A1 (0.42) | ALDH1A1GLAHPGDKDM4EHSD17B10 | |
| SCHEMBL680853 | 0.71 | NPC1 (0.45) | ALDH1A1GLAHPGDKDM4EGAA | |
| SCHEMBL4924089 | 0.71 | KDM4E (0.48) | KDM4EHSD17B10CYP1A2ALOX15SMN1; SMN2 | |
| SCHEMBL302153 | 0.70 | EGFR (0.40) | ALDH1A1GLAHPGDKDM4EGAA | |
| Hydrochloric Acid SCHEMBL4456673 | 0.70 | NPC1 (0.44) | ALDH1A1GLAHPGDKDM4EGAA | |
| SCHEMBL29240141 | 0.69 | GSK3B (0.41) | ALDH1A1GLAHPGDKDM4EGAA | |
| SCHEMBL4875480 | 0.68 | KDM4E (0.36) | ALDH1A1GLAHPGDKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018048930-A1 | LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA, INC. (US) | 2018-03-15 | — | — | WO | claimed |