Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | F2RL3 | Q96RI0 | 3/20 | 0.44 |
| ▸ | FBP1 | P09467 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | GRK6 | P43250 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4905164 | 0.88 | LOXL2 (0.55) | NPC1RAB9AGFERF2RL3FBP1 | |
| SCHEMBL11337498 | 0.87 | NPC1 (0.47) | NPC1RAB9AGFERF2RL3FBP1 | |
| SCHEMBL21341477 | 0.85 | GAA (0.52) | NPC1RAB9AGFERF2RL3FBP1 | |
| SCHEMBL30612627 | 0.84 | PON1 (0.46) | NPC1RAB9AGFERF2RL3FBP1 | |
| SCHEMBL485730 | 0.84 | PON1 (0.46) | NPC1RAB9AGFERF2RL3FBP1 | |
| SCHEMBL30358398 | 0.81 | NPC1 (0.46) | NPC1RAB9AGFERF2RL3FBP1 | |
| SCHEMBL28876443 | 0.81 | NPC1 (0.46) | NPC1RAB9AGFERF2RL3FBP1 | |
| SCHEMBL31070857 | 0.80 | NPC1 (0.42) | NPC1RAB9AGFERF2RL3FBP1 | |
| SCHEMBL6555412 | 0.80 | NPC1 (0.42) | NPC1RAB9AGFERF2RL3FBP1 | |
| SCHEMBL25054111 | 0.79 | NPC1 (0.47) | NPC1RAB9AGFERF2RL3FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018048930-A1 | LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA, INC. (US) | 2018-03-15 | — | — | WO | claimed |
| WO-2018048930-A1 | LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA, INC. (US) | 2018-03-15 | — | — | WO | disclosed |