SCHEMBL19953455

SCHEMBL19953455

CC(C)(C)C(c1ccc(O)cc1)C(C(=O)O)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.43
ESR1 P03372 9/20 0.40
ESR2 Q92731 8/20 0.40
PDCD1 Q15116 1/20 0.40
CD274 Q9NZQ7 1/20 0.40
ALDH1A1 P00352 3/20 0.40
TDP1 Q9NUW8 2/20 0.40
GAA P10253 1/20 0.40
KMT2A Q03164 1/20 0.40
CYP3A4 P08684 5/20 0.37
BLM P54132 1/20 0.37
CYP2C9 P11712 3/20 0.36
CYP2C19 P33261 2/20 0.36
HSD17B10 Q99714 2/20 0.36
LMNA P02545 2/20 0.36
AR P10275 2/20 0.36
DRD1 P21728 2/20 0.36
SLC6A2 P23975 2/20 0.36
SLC6A3 Q01959 2/20 0.36
CYP1A2 P05177 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28395624 0.83 SRC (0.42) SRCESR1ESR2PDCD1CD274
SCHEMBL10656849 0.81 BLM (0.45) SRCESR1ESR2PDCD1CD274
SCHEMBL7899034 0.81 BLM (0.45) SRCESR1ESR2PDCD1CD274
SCHEMBL7531194 0.81 ESR1 (0.40) SRCESR1ESR2ALDH1A1TDP1
SCHEMBL8065325 0.77 ESR1 (0.54) ESR1ESR2PDCD1CD274ALDH1A1
SCHEMBL4630315 0.76 SRC (0.46) SRCESR1ESR2PDCD1CD274
SCHEMBL16682784 0.76 SRC (0.46) SRCESR1ESR2PDCD1CD274
SCHEMBL28029901 0.75 ESR1 (0.52) ESR1ESR2PDCD1CD274ALDH1A1
SCHEMBL21822079 0.74 ESR1 (0.38) SRCESR1ESR2PDCD1CD274
SCHEMBL9352389 0.74 ESR1 (0.42) ESR1ESR2PDCD1CD274TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3510093-A1 ADDITIVE MIXTURE BASF SE (DE) 2019-07-17 EP disclosed
WO-2018046301-A1 ADDITIVE MIXTURE BASF SE (DE) 2018-03-15 WO disclosed