SCHEMBL8065325

SCHEMBL8065325

CC(C)C(c1ccc(O)cc1)C(C)(C)C

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 11/20 0.54
ESR2 Q92731 9/20 0.54
PDCD1 Q15116 1/20 0.54
CD274 Q9NZQ7 1/20 0.54
LMNA P02545 3/20 0.43
CYP3A4 P08684 3/20 0.43
AR P10275 2/20 0.43
SLC6A2 P23975 2/20 0.43
SLC6A3 Q01959 2/20 0.43
MAPT P10636 2/20 0.43
ALOX15 P16050 2/20 0.43
CYP2C9 P11712 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
CYP1A2 P05177 1/20 0.43
PGR P06401 1/20 0.43
CHRM2 P08172 1/20 0.43
ADORA3 P0DMS8 1/20 0.43
CYP2D6 P10635 1/20 0.43
CHRM1 P11229 1/20 0.43
DRD1 P21728 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19490501 0.85 ESR1 (0.48) ESR1ESR2PDCD1CD274LMNA
SCHEMBL20643219 0.80 CYP2C9 (0.49) ESR1ESR2PDCD1CD274CYP3A4
SCHEMBL9352389 0.78 ESR1 (0.42) ESR1ESR2PDCD1CD274LMNA
SCHEMBL14411802 0.78 ESR1 (0.56) ESR1ESR2PDCD1CD274LMNA
SCHEMBL8751432 0.78 ESR1 (0.56) ESR1ESR2PDCD1CD274LMNA
SCHEMBL71466 0.77 ESR1 (0.62) ESR1ESR2PDCD1CD274LMNA
SCHEMBL19953455 0.77 SRC (0.43) ESR1ESR2PDCD1CD274LMNA
SCHEMBL14652607 0.77 ESR1 (0.41) ESR1ESR2PDCD1CD274LMNA
SCHEMBL12859054 0.76 ADRB2 (0.50) LMNASLC6A2SLC6A3TDP1HPGD
SCHEMBL28395624 0.76 SRC (0.42) ESR1ESR2PDCD1CD274LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104508031-B Phosphite compositions 瑞士新集团有限公司 2020-10-16 CN disclosed
CN-104884524-B Stabilized high-density polyethylene composition with improved resistance to deterioration and stabilizer system 伊奎斯塔化学有限公司 2018-07-13 CN disclosed
EP-0628595-B1 Organic phosphite ester compositions containing hindered piperidinyl light stabilizers GEN ELECTRIC (US) 2000-08-23 EP disclosed
EP-0628595-A1 Organic phosphite ester compositions containing hindered piperidinyl light stabilizers GENERAL ELECTRIC COMPANY (US) 1994-12-14 EP disclosed
US-5342978-A Organic phosphite ester compositions containing hindered piperdinyl light stabilizers GENERAL ELECTRIC COMPANY (US) 1994-08-30 US disclosed