Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 2/20 | 0.71 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.71 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.71 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.71 |
| ▸ | AHCY | P23526 | 1/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.62 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.59 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.59 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.59 |
| ▸ | AMD1 | P17707 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.47 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.47 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.47 |
| ▸ | GAPDH | P04406 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16141172 | 1.00 | PI4KA (0.71) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL23120996 | 1.00 | PI4KA (0.71) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL13435086 | 1.00 | PI4KA (0.71) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL13623625 | 1.00 | PI4KA (0.71) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL13610771 | 1.00 | PI4KA (0.71) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL24450953 | 0.87 | PI4KA (0.53) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL16976156 | 0.86 | PI4KA (0.58) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL15381063 | 0.86 | PI4KA (0.58) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL9940772 | 0.84 | PI4KA (0.82) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL12928304 | 0.84 | PI4KA (0.82) | PI4KAPI4K2BPI4K2API4KBAHCY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9914924-B2 | Methods and compositions for treating neurological disease | UNIVERSITY OF MASSACHUSETTS (US) | 2018-03-13 | — | — | US | disclosed |