Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.53 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.53 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.53 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.53 |
| ▸ | AHCY | P23526 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.47 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.47 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.47 |
| ▸ | AMD1 | P17707 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.36 |
| ▸ | ADK | P55263 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19953837 | 0.87 | PI4KA (0.71) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL16141172 | 0.87 | PI4KA (0.71) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL13610771 | 0.87 | PI4KA (0.71) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL23120996 | 0.87 | PI4KA (0.71) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL13435086 | 0.87 | PI4KA (0.71) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL13623625 | 0.87 | PI4KA (0.71) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL24450945 | 0.84 | PI4KA (0.74) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL24450655 | 0.84 | PI4KA (0.61) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL19443155 | 0.82 | CCNB2 (0.47) | PI4KAPI4K2BPI4K2API4KBTDP1 | |
| SCHEMBL13834839 | 0.82 | CCNB2 (0.47) | PI4KAPI4K2BPI4K2API4KBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220162209-A1 | SALICYL-ADENOSINEMONOSULFAMATE ANALOGS AND USES THEREOF | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2022-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220162209-A1 | SALICYL-ADENOSINEMONOSULFAMATE ANALOGS AND USES THEREOF | ADSL, SLC35B2, ADORA1 | PI4KA 4470/4885PI4K2B 4804/4885PI4K2A 4831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.