Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 2/20 | 0.66 |
| ▸ | AKT2 | P31751 | 2/20 | 0.66 |
| ▸ | NPC1 | O15118 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.53 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.53 |
| ▸ | USP7 | Q93009 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.50 |
| ▸ | NR1I3 | Q14994 | 2/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13599904 | 1.00 | AKT1 (0.66) | AKT1AKT2NPC1RAB9AADRA1B | |
| SCHEMBL5347018 | 0.96 | NPC1 (0.66) | AKT1AKT2NPC1RAB9AADRA1B | |
| SCHEMBL22673557 | 0.95 | AKT1 (0.61) | AKT1AKT2NPC1RAB9AADRA1B | |
| SCHEMBL22673697 | 0.95 | AKT1 (0.61) | AKT1AKT2NPC1RAB9AADRA1B | |
| SCHEMBL25789175 | 0.95 | AKT1 (0.61) | AKT1AKT2NPC1RAB9AADRA1B | |
| SCHEMBL24479218 | 0.95 | AKT1 (0.61) | AKT1AKT2NPC1RAB9AADRA1B | |
| SCHEMBL24479413 | 0.95 | AKT1 (0.61) | AKT1AKT2NPC1RAB9AADRA1B | |
| SCHEMBL24478955 | 0.95 | AKT1 (0.61) | AKT1AKT2NPC1RAB9AADRA1B | |
| SCHEMBL22673441 | 0.95 | AKT1 (0.61) | AKT1AKT2NPC1RAB9AADRA1B | |
| SCHEMBL25789166 | 0.95 | AKT1 (0.61) | AKT1AKT2NPC1RAB9AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9917270-B1 | Organic electroluminescent device having an exciton quenching layer | CYNORA GMBH (DE) | 2018-03-13 | — | — | US | disclosed |
| US-9917270-B1 | Organic electroluminescent device having an exciton quenching layer | CYNORA GMBH (DE) | 2018-03-13 | — | — | US | disclosed |