Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 2/20 | 0.61 |
| ▸ | AKT2 | P31751 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.49 |
| ▸ | USP7 | Q93009 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | NR1I3 | Q14994 | 2/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15382851 | 1.00 | AKT1 (0.61) | AKT1AKT2NPC1RAB9AADRA1B | |
| SCHEMBL22673697 | 1.00 | AKT1 (0.61) | AKT1AKT2NPC1RAB9AADRA1B | |
| SCHEMBL25789166 | 1.00 | AKT1 (0.61) | AKT1AKT2NPC1RAB9AADRA1B | |
| SCHEMBL25789364 | 1.00 | AKT1 (0.61) | AKT1AKT2NPC1RAB9AADRA1B | |
| SCHEMBL22673441 | 1.00 | AKT1 (0.61) | AKT1AKT2NPC1RAB9AADRA1B | |
| SCHEMBL24479413 | 1.00 | AKT1 (0.61) | AKT1AKT2NPC1RAB9AADRA1B | |
| SCHEMBL25789175 | 1.00 | AKT1 (0.61) | AKT1AKT2NPC1RAB9AADRA1B | |
| SCHEMBL24478955 | 1.00 | AKT1 (0.61) | AKT1AKT2NPC1RAB9AADRA1B | |
| SCHEMBL22673557 | 1.00 | AKT1 (0.61) | AKT1AKT2NPC1RAB9AADRA1B | |
| SCHEMBL24479406 | 0.98 | AKT1 (0.63) | AKT1AKT2NPC1RAB9AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220169661-A1 | IMIDAZO NITROGEN HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD (CN) | 2022-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220169661-A1 | IMIDAZO NITROGEN HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | HCN4, IPO8, HCN1 | AKT1 2630/4885AKT2 2749/4885NPC1 461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.