Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.82 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.59 |
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 2/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28332015 | 0.98 | CHRM2 (0.85) | CHRM2SCN8AMEN1KMT2AKDM4E | |
| SCHEMBL3265492 | 0.95 | CHRM2 (0.79) | CHRM2SCN8AMEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL27669854 | 0.94 | CHRM2 (0.77) | CHRM2SCN8AMEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL6127176 | 0.90 | CHRM2 (0.94) | CHRM2SCN8AMEN1KMT2AKDM4E | |
| SCHEMBL10384415 | 0.89 | CHRM2 (0.73) | CHRM2SCN8AMEN1KMT2AKDM4E | |
| SCHEMBL4916089 | 0.87 | CHRM2 (0.81) | CHRM2SCN8AMEN1KMT2AKDM4E | |
| SCHEMBL3164467 | 0.86 | CHRM2 (0.66) | CHRM2BCHE | |
| SCHEMBL5678830 | 0.86 | CHRM2 (0.66) | CHRM2KDM4EALDH1A1EPHX2 | |
| SCHEMBL4916807 | 0.85 | CHRM2 (0.84) | CHRM2SCN8AMEN1KMT2AKDM4E | |
| SCHEMBL4917384 | 0.85 | CHRM2 (0.84) | CHRM2SCN8AMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107056799-A | The double heptene sulfamide compounds of suberic acid monoanilide group oxygen bridge, its synthetic method, using and anti-breast cancer medicines composition | 武汉宏兹生物技术有限公司 | 2017-08-18 | — | — | CN | claimed |
| US-9914740-B2 | Tricyclic pyrido-carboxamide derivatives as rock inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-03-13 | — | — | US | disclosed |
| CN-107056799-A | The double heptene sulfamide compounds of suberic acid monoanilide group oxygen bridge, its synthetic method, using and anti-breast cancer medicines composition | 武汉宏兹生物技术有限公司 | 2017-08-18 | — | — | CN | disclosed |