Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.85 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.55 |
| ▸ | FAAH | O00519 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19954201 | 0.98 | CHRM2 (0.82) | CHRM2SCN8ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL3265492 | 0.94 | CHRM2 (0.79) | CHRM2SCN8ACYP1A2CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL27669854 | 0.92 | CHRM2 (0.77) | CHRM2SCN8ACYP1A2CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL6127176 | 0.92 | CHRM2 (0.94) | CHRM2SCN8ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL10384415 | 0.87 | CHRM2 (0.73) | CHRM2SCN8AMEN1KMT2AKDM4E | |
| SCHEMBL16260103 | 0.87 | CHRM2 (0.83) | CHRM2SCN8AMEN1KMT2AKDM4E | |
| SCHEMBL27728328 | 0.87 | CHRM2 (0.68) | CHRM2CYP2D6EPHX2BCHESLC2A1 | |
| SCHEMBL17283414 | 0.87 | CHRM2 (0.68) | CHRM2CYP2D6EPHX2BCHESLC2A1 | |
| SCHEMBL9257479 | 0.85 | CYP1A2 (0.76) | CHRM2CYP1A2CYP2D6CYP2C19MEN1 | |
| SCHEMBL15859362 | 0.85 | CYP1A2 (0.76) | CHRM2CYP1A2CYP2D6CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110538170-A | Application of macamides compound or salt thereof in preparation of medicine for preventing or treating hepatic fibrosis diseases | UNIV SOUTH CHINA | 2019-12-06 | — | — | CN | disclosed |