Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R46 | P59540 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | TAS2R31 | P59538 | 2/20 | 0.31 |
| ▸ | TAS2R10 | Q9NYW0 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13105411 | 0.85 | POLB (0.36) | TAS2R46CYP2C9MEN1KMT2ACHRM5 | |
| SCHEMBL17931566 | 0.80 | LMNA (0.44) | LMNAGBA1THRBCYP2C19PTPN1 | |
| SCHEMBL6933816 | 0.80 | LMNA (0.44) | LMNAGBA1THRBCYP2C19PTPN1 | |
| SCHEMBL20143414 | 0.80 | LMNA (0.44) | LMNAGBA1THRBCYP2C19PTPN1 | |
| SCHEMBL20707209 | 0.80 | LMNA (0.44) | LMNAGBA1THRBCYP2C19PTPN1 | |
| SCHEMBL15895449 | 0.80 | LMNA (0.44) | LMNAGBA1THRBCYP2C19PTPN1 | |
| SCHEMBL22628561 | 0.80 | LMNA (0.44) | LMNAGBA1THRBCYP2C19PTPN1 | |
| SCHEMBL12487623 | 0.78 | — | — | |
| SCHEMBL8379856 | 0.78 | — | — | |
| SCHEMBL10265356 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9914724-B2 | C-aryl glycosid derivatives, pharmaceutical composition, preparation process and uses thereof | Shanghai De Novo Pharmatech Co., Ltd. (CN) | 2018-03-13 | — | — | US | disclosed |