SCHEMBL1995437

SCHEMBL1995437

CCCCCOC(=O)c1ccc(C(=O)Br)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.69
NPC1 O15118 1/20 0.69
MAPT P10636 1/20 0.69
RAB9A P51151 1/20 0.69
TSHR P16473 4/20 0.65
LMNA P02545 3/20 0.65
ESR1 P03372 3/20 0.65
CYP1A2 P05177 2/20 0.65
CYP2C19 P33261 2/20 0.65
MAPK1 P28482 2/20 0.65
CYP2D6 P10635 1/20 0.65
NR1H2 P55055 1/20 0.65
RNASEL Q05823 1/20 0.65
SMN1; SMN2 Q16637 1/20 0.65
CYP3A4 P08684 2/20 0.63
CYP2C9 P11712 1/20 0.63
PDE4D Q08499 1/20 0.63
STS P08842 6/20 0.60
TP53 P04637 1/20 0.57
HPGD P15428 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1992499 0.98 ALDH1A1 (0.71) ALDH1A1NPC1MAPTRAB9ATSHR
SCHEMBL1994616 0.95 ESR1 (0.72) ALDH1A1NPC1MAPTRAB9ATSHR
SCHEMBL1994995 0.91 ALDH1A1 (0.80) ALDH1A1NPC1MAPTRAB9ATSHR
SCHEMBL828600 0.89 ALDH1A1 (0.83) ALDH1A1NPC1MAPTRAB9ATSHR
SCHEMBL9355782 0.89 ALDH1A1 (0.83) ALDH1A1NPC1MAPTRAB9ATSHR
SCHEMBL108532 0.89 ALDH1A1 (0.83) ALDH1A1NPC1MAPTRAB9ATSHR
SCHEMBL9629329 0.89 TSHR (0.79) ALDH1A1NPC1MAPTRAB9ATSHR
SCHEMBL197446 0.89 ALDH1A1 (0.83) ALDH1A1NPC1MAPTRAB9ATSHR
SCHEMBL21048393 0.89 ALDH1A1 (0.83) ALDH1A1NPC1MAPTRAB9ATSHR
SCHEMBL108412 0.89 ALDH1A1 (0.83) ALDH1A1NPC1MAPTRAB9ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8773745-B2 Electrochromic material KYUSHU UNIVERSITY (JP) 2014-07-08 US disclosed
US-20110149367-A1 ELECTROCHROMIC MATERIAL KYUSHU UNIVERSITY (JP) 2011-06-23 US disclosed