Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 3/20 | 0.38 |
| ▸ | DPP4 | P27487 | 8/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.38 |
| ▸ | BTK | Q06187 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19954520 | 0.88 | KDM5A (0.39) | KDM5AMAPTHPGDNPSR1ALDH1A1 | |
| SCHEMBL18163941 | 0.87 | KDM5A (0.45) | KDM5ADPP4DPP7BTKPGR | |
| SCHEMBL19954568 | 0.85 | IRAK4 (0.38) | KDM5AMAPTHPGDNPSR1ALDH1A1 | |
| SCHEMBL19954626 | 0.84 | KDM4E (0.43) | KDM5AMAPTHPGDNPSR1ALDH1A1 | |
| SCHEMBL18161158 | 0.83 | KDM5A (0.50) | KDM5ABTKPIK3R1PIK3CA | |
| SCHEMBL19954599 | 0.81 | NR3C2 (0.39) | MAPTHPGDNPSR1ALDH1A1THRB | |
| SCHEMBL19954594 | 0.81 | GAA (0.46) | KDM5A | |
| SCHEMBL19954569 | 0.81 | PKM (0.41) | DPP4CYP2C9MAPTHPGDNPSR1 | |
| SCHEMBL19954630 | 0.81 | NR3C2 (0.36) | KDM5AMAPTHPGDNPSR1ALDH1A1 | |
| SCHEMBL19954655 | 0.80 | GAA (0.36) | KMT2ANR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10392350-B2 | N-substituted pyrazolyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2019-08-27 | — | — | US | disclosed |
| US-20180222867-A1 | N-SUBSTITUTED PYRAZOLYL GUANIDINE F1F0-ATPASE INHIBITORS AND THERAPEUTIC USES THEREOF | LYCERA CORPORATION | 2018-08-09 | — | — | US | disclosed |
| US-9914706-B2 | N-substituted pyrazolyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2018-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10392350-B2 | N-substituted pyrazolyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | ATP5F1A, ATP5ME, ATP5F1D | KDM5A 2043/4885DPP4 2898/4885DPP7 3710/4885 |
| US-20180222867-A1 | N-SUBSTITUTED PYRAZOLYL GUANIDINE F1F0-ATPASE INHIBITORS AND THERAPEUTIC USES THEREOF | ATP5F1A, ATP5ME, ATP5F1D | KDM5A 2043/4885DPP4 2898/4885DPP7 3710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.