SCHEMBL19954767

SCHEMBL19954767

CCCC(C)(N)C(C)(CC)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.42
KCNN4 O15554 2/20 0.39
SLC6A2 P23975 1/20 0.38
KIF11 P52732 5/20 0.37
MAPK1 P28482 1/20 0.35
MAPT P10636 1/20 0.35
KMT2A Q03164 1/20 0.35
CYP2C19 P33261 2/20 0.34
HIF1A Q16665 1/20 0.34
ALDH1A1 P00352 1/20 0.33
ALOX15 P16050 1/20 0.33
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
TSHR P16473 1/20 0.33
NFKB1 P19838 1/20 0.33
SCN1A P35498 1/20 0.33
MTOR P42345 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1059924 0.83 TAAR1 (0.46) TAAR1KCNN4KIF11MAPK1MAPT
SCHEMBL813383 0.81 TAAR1 (0.41) TAAR1KCNN4KIF11MAPK1CYP2C19
SCHEMBL474982 0.78 TAAR1 (0.50) TAAR1KCNN4MAPK1MAPTKMT2A
SCHEMBL28807710 0.77 TAAR1 (0.46) TAAR1KCNN4SLC6A2KIF11MAPK1
SCHEMBL157809 0.76 KCNN4 (0.48) TAAR1KCNN4SLC6A2KIF11MAPK1
SCHEMBL7598601 0.76 TAAR1 (0.38) TAAR1KCNN4KIF11MAPK1KMT2A
SCHEMBL19954765 0.74 TAAR1 (0.41) TAAR1KCNN4SLC6A2KIF11MAPK1
SCHEMBL9756593 0.74 KCNN4 (0.46) TAAR1KCNN4SLC6A2KIF11MAPK1
Bromide SCHEMBL10687152 0.74 KCNN4 (0.46) TAAR1KCNN4SLC6A2KIF11MAPK1
SCHEMBL19954685 0.74 TAAR1 (0.48) TAAR1KCNN4SLC6A2MAPK1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9917273-B2 Cross-linking polymer and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2018-03-13 US disclosed