SCHEMBL19954853

SCHEMBL19954853

CC1(C)C(/C=C/C2=C(Cl)/C(=C/C=C3/N(CCCCCC(=O)O)c4ccc5ccccc5c4C3(C)C)CC2)=[N+](CCCCCC(=O)O)c2ccc3ccccc3c21

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 10/20 0.56
BLM P54132 1/20 0.55
PRMT5 O14744 1/20 0.55
PRMT8 Q9NR22 1/20 0.55
MLNR O43193 1/20 0.54
NR1I2 O75469 1/20 0.54
PGR P06401 1/20 0.54
ADRB1 P08588 1/20 0.54
ADORA3 P0DMS8 1/20 0.54
CHRM1 P11229 1/20 0.54
DRD2 P14416 1/20 0.54
ADRA2B P18089 1/20 0.54
ADRA2C P18825 1/20 0.54
CHRM3 P20309 1/20 0.54
CNR1 P21554 1/20 0.54
DRD1 P21728 1/20 0.54
TBXA2R P21731 1/20 0.54
SLC6A2 P23975 1/20 0.54
HRH2 P25021 1/20 0.54
HTR2C P28335 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18518584 0.97 PRMT1 (0.56) PRMT1BLMPRMT5PRMT8MLNR
SCHEMBL15026331 0.93 PRMT1 (0.53) PRMT1BLMPRMT5PRMT8MLNR
SCHEMBL31570 0.93 PRMT1 (0.53) PRMT1BLMPRMT5PRMT8MLNR
SCHEMBL19978255 0.93 PRMT1 (0.54) PRMT1BLMPRMT5PRMT8MLNR
SCHEMBL10110723 0.92 PRMT1 (0.56) PRMT1BLMPRMT5PRMT8MLNR
SCHEMBL14597401 0.91 PRMT1 (0.65) PRMT1BLMPRMT5PRMT8MLNR
SCHEMBL26322325 0.90 PRMT1 (0.49) PRMT1BLMPRMT5PRMT8MLNR
SCHEMBL821485 0.90 PRMT1 (0.66) PRMT1BLMPRMT5PRMT8MLNR
SCHEMBL12261677 0.89 PRMT1 (0.54) PRMT1BLMPRMT5PRMT8MLNR
SCHEMBL7601285 0.88 PRMT1 (0.71) PRMT1BLMPRMT5PRMT8MLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9915757-B1 Increased thermal stabilization of optical absorbers THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2018-03-13 US disclosed