SCHEMBL31570

SCHEMBL31570

CC1(C)C(/C=C/C2=C(Cl)/C(=C/C=C3\N(CCCCCC(=O)O)c4ccc5ccccc5c4C3(C)C)CCC2)=[N+](CCO)c2ccc3ccccc3c21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 9/20 0.53
PRMT5 O14744 1/20 0.51
PRMT8 Q9NR22 1/20 0.51
BLM P54132 1/20 0.50
MLNR O43193 1/20 0.49
NR1I2 O75469 1/20 0.49
PGR P06401 1/20 0.49
ADRB1 P08588 1/20 0.49
ADORA3 P0DMS8 1/20 0.49
CHRM1 P11229 1/20 0.49
DRD2 P14416 1/20 0.49
ADRA2B P18089 1/20 0.49
ADRA2C P18825 1/20 0.49
CHRM3 P20309 1/20 0.49
CNR1 P21554 1/20 0.49
DRD1 P21728 1/20 0.49
TBXA2R P21731 1/20 0.49
SLC6A2 P23975 1/20 0.49
HRH2 P25021 1/20 0.49
HTR2C P28335 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15026331 1.00 PRMT1 (0.53) PRMT1PRMT5PRMT8BLMMLNR
SCHEMBL18518584 0.96 PRMT1 (0.56) PRMT1PRMT5PRMT8BLMMLNR
SCHEMBL15026319 0.95 PRMT1 (0.51) PRMT1PRMT5PRMT8BLMMLNR
SCHEMBL10110723 0.94 PRMT1 (0.56) PRMT1PRMT5PRMT8BLMMLNR
SCHEMBL19954853 0.93 PRMT1 (0.56) PRMT1PRMT5PRMT8BLMMLNR
SCHEMBL12261677 0.91 PRMT1 (0.54) PRMT1PRMT5PRMT8BLMMLNR
SCHEMBL19749086 0.91 PRMT1 (0.47) PRMT1PRMT5PRMT8BLMMLNR
SCHEMBL761512 0.90 PRMT1 (0.54) PRMT1PRMT5PRMT8BLMMLNR
SCHEMBL26322325 0.90 PRMT1 (0.49) PRMT1PRMT5PRMT8BLMMLNR
SCHEMBL19978255 0.88 PRMT1 (0.54) PRMT1PRMT5PRMT8BLMMLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9370589-B2 Switching fluorescent nanoparticle probe and fluorescent particle imaging method using same SHIMADZU CORPORATION (JP) 2016-06-21 US disclosed
US-20130149252-A1 SWITCHING FLUORESCENT NANOPARTICLE PROBE AND FLUORESCENT PARTICLE IMAGING METHOD USING SAME KYOTO UNIVERSITY (JP) 2013-06-13 US disclosed
WO-2012026316-A1 SWITCHING FLUORESCENT NANOPARTICLE PROBE AND FLUORESCENT PARTICLE IMAGING METHOD USING SAME 株式会社 島津製作所 (JP) 2012-03-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130149252-A1 SWITCHING FLUORESCENT NANOPARTICLE PROBE AND FLUORESCENT PARTICLE IMAGING METHOD USING SAME TNNI3, TTN, TNNT2 PRMT1 593/4885PRMT5 904/4885PRMT8 1984/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.