Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SCN4A | P35499 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19308855 | 0.92 | NPC1 (0.34) | NPC1SCN4ARAB9ASMN1; SMN2PARP15 | |
| SCHEMBL827121 | 0.81 | RAB9A (0.44) | NPC1SCN4ARAB9ASMN1; SMN2PARP15 | |
| SCHEMBL3798602 | 0.78 | GAA (0.42) | NPC1RAB9ASMN1; SMN2HDAC2HDAC8 | |
| SCHEMBL827789 | 0.76 | NPC1 (0.41) | NPC1SCN4ARAB9ASMN1; SMN2PARP15 | |
| SCHEMBL22758445 | 0.73 | CYP2A6 (0.33) | NPC1SCN4ARAB9ASMN1; SMN2 | |
| SCHEMBL24421194 | 0.72 | SMN1; SMN2 (0.32) | NPC1SCN4ARAB9ASMN1; SMN2 | |
| SCHEMBL24253705 | 0.71 | HSP90AB1 (0.34) | — | |
| SCHEMBL3799813 | 0.70 | CYP2A6 (0.46) | NPC1SCN4ARAB9ASMN1; SMN2 | |
| SCHEMBL19120041 | 0.69 | OGA (0.37) | NPC1SCN4ARAB9ASMN1; SMN2 | |
| Butane SCHEMBL827112 | 0.68 | CYP2A6 (0.44) | NPC1SCN4ARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9913855-B2 | Uridine diphosphate derivatives, prodrugs, compositions and uses thereof | TUFTS UNIVERSITY (US) | 2018-03-13 | — | — | US | disclosed |