Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL2RA | P01589 | 1/20 | 0.74 |
| ▸ | ALB | P02768 | 1/20 | 0.74 |
| ▸ | IL2 | P60568 | 1/20 | 0.74 |
| ▸ | F2 | P00734 | 12/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.47 |
| ▸ | YAP1 | P46937 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20761277 | 0.95 | IL2RA (0.71) | IL2RAALBIL2F2ITGB1 | |
| SCHEMBL15159835 | 0.92 | IL2RA (0.77) | IL2RAALBIL2F2ITGB1 | |
| SCHEMBL4323694 | 0.88 | IL2RA (0.84) | IL2RAALBIL2F2ITGB1 | |
| SCHEMBL4323700 | 0.88 | IL2RA (0.84) | IL2RAALBIL2F2ITGB1 | |
| SCHEMBL4323684 | 0.88 | IL2RA (0.84) | IL2RAALBIL2F2ITGB1 | |
| SCHEMBL4993522 | 0.88 | IL2RA (0.84) | IL2RAALBIL2F2ITGB1 | |
| SCHEMBL14136720 | 0.85 | IL2RA (1.00) | IL2RAALBIL2ITGB1ITGA4 | |
| SCHEMBL6860593 | 0.85 | IL2RA (1.00) | IL2RAALBIL2ITGB1ITGA4 | |
| SCHEMBL14136732 | 0.85 | IL2RA (1.00) | IL2RAALBIL2ITGB1ITGA4 | |
| SCHEMBL6860596 | 0.85 | IL2RA (1.00) | IL2RAALBIL2ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9913826-B2 | Compounds and compositions that bind and stabilize transthyretin and their use for inhibiting transthyretin amyloidosis and protein-protein interactions | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2018-03-13 | — | — | US | disclosed |