Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL2RA | P01589 | 1/20 | 0.71 |
| ▸ | ALB | P02768 | 1/20 | 0.71 |
| ▸ | IL2 | P60568 | 1/20 | 0.71 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 13/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | YAP1 | P46937 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19954949 | 0.95 | IL2RA (0.74) | IL2RAALBIL2ITGB1ITGA4 | |
| SCHEMBL15159835 | 0.90 | IL2RA (0.77) | IL2RAALBIL2ITGB1ITGA4 | |
| SCHEMBL4323694 | 0.86 | IL2RA (0.84) | IL2RAALBIL2ITGB1ITGA4 | |
| SCHEMBL4323700 | 0.86 | IL2RA (0.84) | IL2RAALBIL2ITGB1ITGA4 | |
| SCHEMBL4993522 | 0.86 | IL2RA (0.84) | IL2RAALBIL2ITGB1ITGA4 | |
| SCHEMBL4323684 | 0.86 | IL2RA (0.84) | IL2RAALBIL2ITGB1ITGA4 | |
| SCHEMBL6860593 | 0.83 | IL2RA (1.00) | IL2RAALBIL2ITGB1ITGA4 | |
| SCHEMBL14136720 | 0.83 | IL2RA (1.00) | IL2RAALBIL2ITGB1ITGA4 | |
| SCHEMBL6860596 | 0.83 | IL2RA (1.00) | IL2RAALBIL2ITGB1ITGA4 | |
| SCHEMBL14136732 | 0.83 | IL2RA (1.00) | IL2RAALBIL2ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190054040-A1 | Identification of Stabilizers of Multimeric Proteins | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2019-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190054040-A1 | Identification of Stabilizers of Multimeric Proteins | TTR, HSPBP1, HSPH1 | IL2RA 2871/4885ALB 11/4885IL2 4359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.