SCHEMBL19954979

SCHEMBL19954979

CC(C)(C)OC(=O)N1CCC[C@@]1(C)c1nc2ccccc2[nH]1

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HCRTR1 O43613 20/20 0.49
HCRTR2 O43614 20/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16779314 0.84 HCRTR1 (0.47) HCRTR1HCRTR2
SCHEMBL16779313 0.84 HCRTR1 (0.47) HCRTR1HCRTR2
SCHEMBL19954967 0.83 HCRTR1 (0.51) HCRTR1HCRTR2
SCHEMBL31589797 0.82 PARP1 (0.68)
SCHEMBL16797989 0.79 HCRTR1 (0.63) HCRTR1HCRTR2
SCHEMBL16797988 0.79 HCRTR1 (0.63) HCRTR1HCRTR2
SCHEMBL26188364 0.79 HCRTR1 (0.47) HCRTR1HCRTR2
SCHEMBL21615603 0.77 PDE10A (0.42)
SCHEMBL16798726 0.76 HCRTR1 (0.44) HCRTR1HCRTR2
SCHEMBL16798727 0.76 HCRTR1 (0.44) HCRTR1HCRTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9914721-B2 Use of benzimidazole-proline derivatives IDORSIA PHARMACEUTICALS LTD (CH) 2018-03-13 US disclosed