Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20079573 | 0.79 | MAPT (0.35) | MAPT | |
| SCHEMBL950901 | 0.79 | SLC2A1 (0.37) | MAPTSLC2A1 | |
| SCHEMBL24022012 | 0.79 | TSHR (0.33) | — | |
| SCHEMBL26512365 | 0.76 | PLA2G1B (0.34) | MAPTSLC2A1 | |
| SCHEMBL5002428 | 0.74 | MEN1 (0.34) | MAPTSLC2A1 | |
| SCHEMBL16549346 | 0.73 | MAPT (0.36) | MAPT | |
| SCHEMBL12022837 | 0.73 | CYP3A4 (0.30) | — | |
| SCHEMBL24299500 | 0.72 | SLC2A1 (0.33) | MAPTSLC2A1 | |
| SCHEMBL1704289 | 0.71 | — | — | |
| SCHEMBL22928952 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3686251-B1 | RADIATION CURABLE INKJET INKS FOR INTERIOR DECORATION | AGFA NV (BE) | 2021-11-17 | — | — | EP | disclosed |
| US-20180094031-A1 | CYCLOSPORIN DERIVATIVES WHEREIN THE MEBMT SIDECHAIN HAS BEEN CYCLIZED | ALLERGAN, INC. | 2018-04-05 | — | — | US | disclosed |
| US-9914755-B2 | Cyclosporin derivatives wherein the MeBmt sidechain has been cyclized | ALLERGAN, INC. (US) | 2018-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180094031-A1 | CYCLOSPORIN DERIVATIVES WHEREIN THE MEBMT SIDECHAIN HAS BEEN CYCLIZED | CHP1, PPIB, FKBP1B | MAPT 1401/4885SLC2A1 2790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.