Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | PHGDH | O43175 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19955072 | 0.79 | MAPT (0.33) | MAPT | |
| SCHEMBL950901 | 0.77 | SLC2A1 (0.37) | MAPTCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL9324816 | 0.73 | MAPT (0.54) | MAPTCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL24022012 | 0.72 | TSHR (0.33) | — | |
| SCHEMBL5002428 | 0.72 | MEN1 (0.34) | MAPTCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL968396 | 0.71 | TDP1 (0.50) | MAPTCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL16549346 | 0.71 | MAPT (0.36) | MAPTCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL24334539 | 0.71 | MAPT (0.39) | MAPTCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL890300 | 0.71 | MAPT (0.50) | MAPTCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL13461104 | 0.71 | CES2 (0.50) | MAPTCHRM2CHRM4CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49233-E1 | Ionizable cationic lipid for RNA delivery | ARCTURUS THERAPEUTICS, INC. (US) | 2022-10-04 | — | — | US | disclosed |
| US-9951002-B2 | Ionizable cationic lipid for RNA delivery | ARCTURUS THERAPEUTICS, INC. (US) | 2018-04-24 | — | — | US | disclosed |