Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 4/20 | 0.54 |
| ▸ | CD74 | P04233 | 2/20 | 0.52 |
| ▸ | MIF | P14174 | 2/20 | 0.52 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | GRK2 | P25098 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.36 |
| ▸ | NEK2 | P51955 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL138490 | 0.80 | MTOR (0.58) | MTORCD74MIFTNIKFYN | |
| SCHEMBL20892260 | 0.80 | MTOR (0.54) | MTORCD74MIFTNIKFYN | |
| SCHEMBL29522354 | 0.80 | MTOR (0.58) | MTORCD74MIFTNIKFYN | |
| SCHEMBL29522322 | 0.76 | MTOR (0.58) | MTORCD74MIFTNIKFYN | |
| SCHEMBL136928 | 0.76 | MTOR (0.58) | MTORCD74MIFTNIKFYN | |
| SCHEMBL20017654 | 0.71 | MTOR (0.47) | MTORTNIKFYNALDH1A1GAA | |
| SCHEMBL25055361 | 0.69 | CD74 (1.00) | MTORCD74MIFL3MBTL1MEN1 | |
| SCHEMBL16432718 | 0.64 | CD74 (0.50) | MTORCD74MIFALDH1A1KDM4E | |
| SCHEMBL28111872 | 0.62 | CD74 (0.52) | MTORCD74MIFL3MBTL1ALDH1A1 | |
| SCHEMBL482032 | 0.62 | CMA1 (0.48) | MTORL3MBTL1ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2825171-B1 | TREATMENT OF CANCER WITH TOR KINASE INHIBITORS | SIGNAL PHARM LLC (US) | 2018-03-14 | — | — | EP | disclosed |