⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8305433 | 0.79 | — | — | |
| SCHEMBL23665511 | 0.79 | ALDH1A1 (0.30) | — | |
| SCHEMBL21694971 | 0.74 | CYP1A2 (0.34) | — | |
| SCHEMBL22081813 | 0.74 | CYP1A2 (0.34) | — | |
| SCHEMBL24469698 | 0.74 | ALDH1A1 (0.33) | — | |
| SCHEMBL24355618 | 0.74 | — | — | |
| SCHEMBL9243457 | 0.74 | CYP1A2 (0.30) | — | |
| SCHEMBL24335385 | 0.74 | — | — | |
| SCHEMBL21549095 | 0.74 | ALDH1A1 (0.38) | — | |
| SCHEMBL24355563 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906246-B1 | VEGF NEUTRALIZING PRODRUGS COMPRISING RANIBIZUMAB FOR THE TREATMENT OF OCULAR CONDITIONS CHARACTERIZED BY OCULAR NEOVASCULARIZATION | ASCENDIS PHARMA OPHTHALMOLOGY DIV A/S (DK) | 2023-07-26 | — | — | EP | disclosed |
| EP-2988732-B1 | MODIFIED HYDROGELS | ASCENDIS PHARMA AS (DK) | 2023-05-03 | — | — | EP | disclosed |
| US-20200277514-A1 | Chemical Mechanical Polishing For Copper And Through Silicon Via Applications | VERSUM MATERIALS US, LLC (US) | 2020-09-03 | — | — | US | disclosed |
| WO-2020034477-A1 | POROUS ORGANIC CAGE LIGAND CONTAINING P AND N, PREPARATION THEREFOR AND USE THEREOF | 中国科学院大连化学物理研究所 | 2020-02-20 | — | — | WO | disclosed |
| EP-2906617-B1 | HYDROGEL PRODRUGS | ASCENDIS PHARMA AS (DK) | 2018-03-14 | — | — | EP | disclosed |