Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25963597 | 0.85 | DPP4 (0.38) | TSHRDPP4GPR88 | |
| SCHEMBL12862582 | 0.82 | DPP4 (0.42) | DPP4GPR88MAPTPOLB | |
| SCHEMBL17354810 | 0.78 | DPP4 (0.37) | DPP4GPR88 | |
| SCHEMBL18900639 | 0.78 | DPP4 (0.37) | DPP4GPR88 | |
| SCHEMBL18377887 | 0.76 | DPP4 (0.44) | DPP4GPR88 | |
| SCHEMBL24346555 | 0.75 | P2RX7 (0.38) | GPR88 | |
| SCHEMBL764212 | 0.74 | — | — | |
| SCHEMBL15214248 | 0.74 | KDM4E (0.38) | LMNADPP4ALDH1A1GPR88 | |
| SCHEMBL24864544 | 0.74 | DPP4 (0.35) | DPP4GPR88 | |
| SCHEMBL20615481 | 0.74 | DPP4 (0.40) | TSHRSMN1; SMN2LMNADPP4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3293182-A1 | HUMAN PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE | Aerpio Therapeutics, Inc. (US) | 2018-03-14 | — | — | EP | disclosed |