Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX4 | Q9NPH5 | 20/20 | 0.73 |
| ▸ | CYBB | P04839 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1303310 | 0.88 | NOX4 (0.62) | NOX4CYBBCYP3A4NOX1CYP2C9 | |
| SCHEMBL1303366 | 0.85 | NOX4 (1.00) | NOX4CYBBCYP3A4NOX1CYP2C9 | |
| SCHEMBL1302583 | 0.83 | NOX4 (0.65) | NOX4CYBBCYP3A4NOX1CYP2C9 | |
| SCHEMBL1302202 | 0.81 | NOX4 (0.62) | NOX4CYBBCYP3A4NOX1CYP2C9 | |
| SCHEMBL1302735 | 0.80 | NOX4 (0.58) | NOX4CYBBCYP3A4NOX1CYP2C9 | |
| SCHEMBL1303177 | 0.79 | NOX4 (0.64) | NOX4CYBBCYP3A4NOX1CYP2C9 | |
| SCHEMBL1302658 | 0.79 | NOX4 (0.80) | NOX4CYBBCYP3A4NOX1CYP2C9 | |
| SCHEMBL1302711 | 0.79 | NOX4 (0.64) | NOX4CYBBCYP3A4NOX1CYP2C9 | |
| SCHEMBL1303061 | 0.78 | NOX4 (0.61) | NOX4CYBBCYP3A4NOX1CYP2C9 | |
| SCHEMBL19956788 | 0.77 | NOX4 (0.54) | NOX4CYBBCYP3A4NOX1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2860179-B1 | Pyrazolo pyridine derivatives as NADPH oxidase inhibitors | GENKYOTEX SUISSE SA (CH) | 2018-03-14 | — | — | EP | disclosed |