Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 11/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.39 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17899889 | 0.74 | SLC22A12 (0.74) | SLC22A12MAPTTDP1SLC22A6SLC22A11 | |
| SCHEMBL14919143 | 0.71 | SLC22A12 (0.74) | SLC22A12SLC22A6SLC22A11ABCG2 | |
| SCHEMBL16247973 | 0.71 | SLC22A12 (0.69) | SLC22A12MAPTTDP1ALDH1A1GAA | |
| SCHEMBL18979023 | 0.70 | SLC22A12 (0.69) | SLC22A12SLC22A6SLC22A11ABCG2 | |
| SCHEMBL9987685 | 0.70 | SLC22A12 (0.75) | SLC22A12MAPTSLC22A6SLC22A11ABCG2 | |
| SCHEMBL28856524 | 0.70 | SLC22A12 (0.44) | SLC22A12MAPTSLC22A6SLC22A11ABCG2 | |
| SCHEMBL21350525 | 0.69 | SLC22A12 (0.77) | SLC22A12SLC22A6SLC22A11ABCG2 | |
| SCHEMBL21350299 | 0.69 | SLC22A12 (0.54) | SLC22A12SLC22A6SLC22A11ABCG2 | |
| SCHEMBL21350512 | 0.67 | SLC22A12 (0.52) | SLC22A12SLC22A6SLC22A11ABCG2 | |
| SCHEMBL9362789 | 0.66 | ALDH1A1 (0.71) | MAPTALDH1A1GAAL3MBTL1NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2998296-B1 | CYCLOALKYL ACID DERIVATIVE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL APPLICATION THEREOF | Shanghai hengrui pharmaceutical co ltd (CN) | 2018-03-14 | — | — | EP | disclosed |