SCHEMBL19958148

SCHEMBL19958148

COc1cc(N=Nc2c(S(=O)(=O)O)cc3cc(Nc4ccc(N)c(S(=O)(=O)O)c4)ccc3c2O)c(O)cc1N=Nc1cc(S(=O)(=O)O)c2cccc(S(=O)(=O)O)c2c1

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ ENPP2 Q13822 11/20 0.53
▸ PHLPP2 Q6ZVD8 2/20 0.50
▸ CD40 P25942 1/20 0.43
▸ CD40LG P29965 1/20 0.43
▸ SENP2 Q9HC62 2/20 0.42
▸ ATIC P31939 1/20 0.42
▸ SUMO2 P61956 1/20 0.42
▸ SUMO1 P63165 1/20 0.42
▸ SENP7 Q9BQF6 1/20 0.42
▸ PRMT1 Q99873 2/20 0.42
▸ PRMT3 O60678 1/20 0.42
▸ EP300 Q09472 1/20 0.42
▸ PRMT6 Q96LA8 1/20 0.42
▸ CARM1 Q86X55 1/20 0.40
▸ SENP1 Q9P0U3 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20746886 0.95 ENPP2 (0.58) ENPP2PHLPP2CD40CD40LGSENP2
SCHEMBL20747577 0.92 ENPP2 (0.63) ENPP2PHLPP2CD40CD40LGPRMT1
SCHEMBL17518424 0.91 ENPP2 (0.55) ENPP2PHLPP2CD40CD40LGSENP2
SCHEMBL17545777 0.89 ENPP2 (0.64) ENPP2PHLPP2CD40CD40LGSENP2
SCHEMBL19235045 0.89 ENPP2 (0.64) ENPP2PHLPP2CD40CD40LGSENP2
SCHEMBL19234937 0.88 ENPP2 (0.59) ENPP2PHLPP2CD40CD40LGPRMT1
SCHEMBL15628312 0.88 ENPP2 (0.60) ENPP2PHLPP2CD40CD40LGSENP2
SCHEMBL17515787 0.88 ENPP2 (0.52) ENPP2PHLPP2CD40CD40LGSENP2
SCHEMBL19958247 0.86 ENPP2 (0.67) ENPP2PHLPP2CD40CD40LGSENP2
SCHEMBL19958190 0.86 ENPP2 (0.51) ENPP2PHLPP2CD40CD40LGSENP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10007142-B2 Dye-based polarizer as well as polarizing plate and liquid crystal display device using the polarizer NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2018-06-26 — — US disclosed
US-20180074371-A1 DYE-BASED POLARIZER AS WELL AS POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE USING THE POLARIZER POLATECHNO CO., LTD. (JP) 2018-03-15 — — US disclosed
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