SCHEMBL19958155

SCHEMBL19958155

COc1ccc(N=Nc2ccc3c(O)c(N=Nc4cc(C)c(N=Nc5ccc(N=Nc6ccc(N=Nc7cc8c(S(=O)(=O)O)cc(S(=O)(=O)O)cc8cc7S(=O)(=O)O)c(C)c6)c(C)c5)cc4C)c(S(=O)(=O)O)cc3c2)cc1N

nearest known ligand 0.62

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 12/20 0.62
MEN1 O00255 1/20 0.50
HTT P42858 1/20 0.50
KMT2A Q03164 1/20 0.50
PHLPP2 Q6ZVD8 2/20 0.48
CD40 P25942 1/20 0.47
CD40LG P29965 1/20 0.47
ALDH1A1 P00352 1/20 0.46
HIF1A Q16665 1/20 0.46
SUMO2 P61956 1/20 0.44
SUMO1 P63165 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
SENP3 Q9H4L4 1/20 0.44
SENP2 Q9HC62 1/20 0.44
SENP1 Q9P0U3 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17460969 0.91 ENPP2 (0.56) ENPP2MEN1HTTKMT2APHLPP2
SCHEMBL15935812 0.90 ENPP2 (0.55) ENPP2MEN1HTTKMT2APHLPP2
SCHEMBL15935810 0.89 ENPP2 (0.57) ENPP2MEN1HTTKMT2APHLPP2
SCHEMBL17460958 0.89 ENPP2 (0.56) ENPP2MEN1HTTKMT2APHLPP2
SCHEMBL15935814 0.88 ENPP2 (0.58) ENPP2MEN1HTTKMT2APHLPP2
SCHEMBL14773825 0.87 ENPP2 (0.57) ENPP2MEN1HTTKMT2APHLPP2
SCHEMBL14773653 0.87 ENPP2 (0.57) ENPP2MEN1HTTKMT2APHLPP2
SCHEMBL14773827 0.86 ENPP2 (0.57) ENPP2MEN1HTTKMT2APHLPP2
SCHEMBL17284054 0.84 ENPP2 (0.56) ENPP2MEN1HTTKMT2APHLPP2
SCHEMBL12174341 0.84 ENPP2 (0.62) ENPP2MEN1HTTKMT2APHLPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10007142-B2 Dye-based polarizer as well as polarizing plate and liquid crystal display device using the polarizer NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2018-06-26 US disclosed
US-20180074371-A1 DYE-BASED POLARIZER AS WELL AS POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE USING THE POLARIZER POLATECHNO CO., LTD. (JP) 2018-03-15 US disclosed