SCHEMBL19958236

SCHEMBL19958236

Cc1cc(N=Nc2cc(O)c(N=Nc3c(S(=O)(=O)O)cc4cc(Nc5ccccc5)ccc4c3O)cc2C)c(C)cc1N=Nc1cc(C)c(N=Nc2ccc(S(=O)(=O)O)cc2S(=O)(=O)O)cc1C

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 10/20 0.69
CD40 P25942 1/20 0.55
CD40LG P29965 1/20 0.55
ALDH1A1 P00352 2/20 0.54
HIF1A Q16665 2/20 0.54
MEN1 O00255 1/20 0.50
THRB P10828 1/20 0.50
KMT2A Q03164 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
PHLPP2 Q6ZVD8 1/20 0.48
CYP1A2 P05177 1/20 0.48
PRMT3 O60678 1/20 0.47
EP300 Q09472 1/20 0.47
PRMT6 Q96LA8 1/20 0.47
PRMT1 Q99873 1/20 0.47
NSD2 O96028 1/20 0.47
DUSP3 P51452 1/20 0.47
PTPN5 P54829 1/20 0.47
CASP7 P55210 1/20 0.47
CASP6 P55212 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19958240 0.98 ENPP2 (0.66) ENPP2CD40CD40LGALDH1A1HIF1A
SCHEMBL12757457 0.97 ENPP2 (0.70) ENPP2CD40CD40LGALDH1A1HIF1A
SCHEMBL19958182 0.96 ENPP2 (0.65) ENPP2CD40CD40LGALDH1A1HIF1A
SCHEMBL20746887 0.96 ENPP2 (0.62) ENPP2CD40CD40LGALDH1A1HIF1A
SCHEMBL19958238 0.94 ENPP2 (0.80) ENPP2CD40CD40LGALDH1A1HIF1A
SCHEMBL19958241 0.94 ENPP2 (0.62) ENPP2CD40CD40LGALDH1A1HIF1A
SCHEMBL17515790 0.93 ENPP2 (0.60) ENPP2CD40CD40LGALDH1A1HIF1A
SCHEMBL15386706 0.92 ENPP2 (0.66) ENPP2CD40CD40LGALDH1A1HIF1A
SCHEMBL19234941 0.92 ENPP2 (0.68) ENPP2CD40CD40LGALDH1A1HIF1A
SCHEMBL14609146 0.92 ENPP2 (0.68) ENPP2CD40CD40LGALDH1A1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10007142-B2 Dye-based polarizer as well as polarizing plate and liquid crystal display device using the polarizer NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2018-06-26 US disclosed
US-20180074371-A1 DYE-BASED POLARIZER AS WELL AS POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE USING THE POLARIZER POLATECHNO CO., LTD. (JP) 2018-03-15 US disclosed