Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.63 |
| ▸ | AKT1 | P31749 | 1/20 | 0.49 |
| ▸ | GJB2 | P29033 | 1/20 | 0.47 |
| ▸ | SELP | P16109 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13449598 | 1.00 | TLR4 (0.63) | TLR4AKT1GJB2SELP | |
| SCHEMBL12837376 | 1.00 | TLR4 (0.63) | TLR4AKT1GJB2SELP | |
| SCHEMBL13449597 | 0.95 | TLR4 (0.69) | TLR4AKT1SELP | |
| SCHEMBL12837127 | 0.95 | TLR4 (0.69) | TLR4AKT1SELP | |
| SCHEMBL29406083 | 0.93 | TLR4 (0.71) | TLR4AKT1SELP | |
| SCHEMBL29381517 | 0.93 | TLR4 (0.71) | TLR4AKT1SELP | |
| SCHEMBL31727702 | 0.93 | TLR4 (0.71) | TLR4AKT1SELP | |
| SCHEMBL13466917 | 0.93 | TLR4 (0.67) | TLR4AKT1SELP | |
| SCHEMBL13449590 | 0.93 | TLR4 (0.67) | TLR4AKT1SELP | |
| Trehalose SCHEMBL7990885 | 0.89 | TLR4 (0.53) | TLR4AKT1GJB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230133705-A1 | TREHALOSE ANALOGUES | CENTRAL MICHIGAN UNIVERSITY | 2023-05-04 | — | — | US | disclosed |
| US-20180072767-A1 | TREHALOSE ANALOGUES | NATIONAL SCIENCE FOUNDATION | 2018-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230133705-A1 | TREHALOSE ANALOGUES | TREH, TALDO1, GALE | TLR4 2106/4885AKT1 3356/4885GJB2 4028/4885 |
| US-20180072767-A1 | TREHALOSE ANALOGUES | TREH, TALDO1, GALE | TLR4 2106/4885AKT1 3356/4885GJB2 4028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.