Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | PRKCG | P05129 | 1/20 | 0.43 |
| ▸ | PRKCB | P05771 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | PRKCH | P24723 | 1/20 | 0.43 |
| ▸ | PRKCI | P41743 | 1/20 | 0.43 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.43 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.43 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.43 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.43 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | IGF2R | P11717 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19961991 | 1.00 | TLR4 (0.46) | TLR4PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL19962537 | 1.00 | TLR4 (0.46) | TLR4PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL19961851 | 0.99 | TLR4 (0.47) | TLR4PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL19958448 | 0.99 | TLR4 (0.47) | TLR4PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL19961853 | 0.99 | TLR4 (0.47) | TLR4PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL19961989 | 0.91 | TLR4 (0.46) | TLR4PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL19958463 | 0.91 | TLR4 (0.46) | TLR4PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL19962807 | 0.91 | TLR4 (0.46) | TLR4PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL24797022 | 0.88 | TLR4 (0.41) | TLR4PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL19958444 | 0.85 | TLR4 (0.48) | TLR4PRKD3PRKCGPRKCBPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230133705-A1 | TREHALOSE ANALOGUES | CENTRAL MICHIGAN UNIVERSITY | 2023-05-04 | — | — | US | disclosed |
| US-20180072767-A1 | TREHALOSE ANALOGUES | NATIONAL SCIENCE FOUNDATION | 2018-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230133705-A1 | TREHALOSE ANALOGUES | TREH, TALDO1, GALE | TLR4 2106/4885PRKD3 3677/4885PRKCG 4097/4885 |
| US-20180072767-A1 | TREHALOSE ANALOGUES | TREH, TALDO1, GALE | TLR4 2106/4885PRKD3 3677/4885PRKCG 4097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.