Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.43 |
| ▸ | EED | O75530 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.34 |
| ▸ | CPN1 | P15169 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5230643 | 1.00 | CHRNB2 (0.43) | CHRNB2CHRNA4EEDCHRNB4CHRNA3 | |
| SCHEMBL19959245 | 1.00 | CHRNB2 (0.43) | CHRNB2CHRNA4EEDCHRNB4CHRNA3 | |
| SCHEMBL5233144 | 0.91 | CHRNB2 (0.43) | CHRNB2CHRNA4EEDCHRNB4CHRNA3 | |
| SCHEMBL5236601 | 0.86 | CHRNB2 (0.43) | CHRNB2CHRNA4EEDCHRNB4CHRNA3 | |
| Tert-Butyl Formate SCHEMBL27675695 | 0.85 | CHRNB2 (0.38) | CHRNB2CHRNA4EEDCHRNB4CHRNA3 | |
| SCHEMBL18183307 | 0.84 | CHRNB2 (0.44) | CHRNB2CHRNA4EEDCHRNB4CHRNA3 | |
| SCHEMBL1484881 | 0.83 | — | — | |
| SCHEMBL1088927 | 0.83 | — | — | |
| SCHEMBL792732 | 0.83 | — | — | |
| SCHEMBL19959091 | 0.82 | CHRNB2 (0.43) | CHRNB2CHRNA4EEDCHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10919856-B2 | Cyclohexene compounds and use thereof | GUANGZHOU HENOVCOM BIOSCIENCE CO. LTD. (CN) | 2021-02-16 | — | — | US | disclosed |
| US-20190241520-A1 | CYCLOHEXENE COMPOUNDS AND USE THEREOF | GUANGZHOU HENOVCOM BIOSCIENCE CO. LTD. (CN) | 2019-08-08 | — | — | US | disclosed |
| WO-2018045950-A1 | CYCLOHEXENE COMPOUNDS AND USE THEREOF | 广州市恒诺康医药科技有限公司 | 2018-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190241520-A1 | CYCLOHEXENE COMPOUNDS AND USE THEREOF | CYP51A1, FURIN, CYP21A2 | CHRNB2 3271/4885CHRNA4 3599/4885EED 4032/4885 |
| US-10919856-B2 | Cyclohexene compounds and use thereof | CYP51A1, FURIN, CYP21A2 | CHRNB2 3271/4885CHRNA4 3599/4885EED 4032/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.