Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MDM4 | O15151 | 1/20 | 0.50 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.50 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 3/20 | 0.44 |
| ▸ | NOS3 | P29474 | 2/20 | 0.44 |
| ▸ | NOS1 | P29475 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19963571 | 0.89 | ATM (0.52) | KMT2ANOS2NOS3NOS1ALDH1A1 | |
| SCHEMBL19951565 | 0.88 | FOLH1 (0.50) | NPSR1ALDH1A1 | |
| SCHEMBL30374583 | 0.86 | GRIA1 (0.39) | NPSR1KMT2AMDM4MDM2ALDH1A1 | |
| SCHEMBL30511873 | 0.85 | NPSR1 (0.56) | NPSR1KMT2AMDM4MDM2LNPEP | |
| SCHEMBL27854966 | 0.85 | NPSR1 (0.56) | NPSR1KMT2AMDM4MDM2LNPEP | |
| SCHEMBL12863003 | 0.81 | MDM4 (0.60) | NPSR1KMT2AMDM4MDM2LNPEP | |
| SCHEMBL19963651 | 0.79 | CYP2C9 (0.33) | KMT2ATSHRALDH1A1 | |
| SCHEMBL19951581 | 0.78 | NPSR1 (0.56) | NPSR1KMT2ANOS2ALDH1A1 | |
| SCHEMBL28582286 | 0.77 | MDM4 (0.58) | NPSR1KMT2AMDM4MDM2LNPEP | |
| SCHEMBL28582287 | 0.77 | MDM4 (0.58) | NPSR1KMT2AMDM4MDM2LNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3510041-B1 | PROCESSES FOR SEPARATING AGGREGATED PROTEINS FROM MONOMERIC PROTEINS IN A BIOLOGICAL SOLUTION | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2023-05-31 | — | — | EP | disclosed |
| WO-2018048698-A1 | PROCESSES FOR SEPARATING AGGREGATED PROTEINS FROM MONOMERIC PROTEINS IN A BIOLOGICAL SOLUTION | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-03-15 | — | — | WO | disclosed |