Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 1/20 | 0.60 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.54 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MIF | P14174 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.47 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28883406 | 0.87 | NOS2 (0.55) | MDM4MDM2KMT2AALDH1A1ATM | |
| SCHEMBL28582286 | 0.87 | MDM4 (0.58) | MDM4MDM2NPSR1KMT2ALNPEP | |
| SCHEMBL6510996 | 0.87 | LNPEP (0.49) | MDM4MDM2NPSR1KMT2ALNPEP | |
| SCHEMBL28883318 | 0.87 | NOS2 (0.61) | MDM4MDM2KMT2ATSHRALDH1A1 | |
| SCHEMBL28883302 | 0.87 | NPSR1 (0.56) | MDM4MDM2NPSR1KMT2ATSHR | |
| SCHEMBL28582287 | 0.87 | MDM4 (0.58) | MDM4MDM2NPSR1KMT2ALNPEP | |
| SCHEMBL12863012 | 0.87 | ATM (0.63) | MDM4MDM2KMT2AALDH1A1ATM | |
| SCHEMBL11940456 | 0.87 | ATM (0.63) | MDM4MDM2KMT2AALDH1A1ATM | |
| SCHEMBL20211752 | 0.87 | ATM (0.63) | MDM4MDM2KMT2AALDH1A1ATM | |
| SCHEMBL28883295 | 0.86 | ALDH1A1 (0.48) | MDM4MDM2NPSR1KMT2ALNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028509-A1 | Sulfonamides | MERCK SERONO SA (CH) | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028509-A1 | Sulfonamides | CXCR3, CXCR2, CXCR1 | MDM4 3549/4885MDM2 2877/4885NPSR1 59/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.