Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HPN | P05981 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30130048 | 0.86 | SMN1; SMN2 (0.56) | SMN1; SMN2HPNKDM4ARAB9ACACNA1H | |
| SCHEMBL19964551 | 0.85 | SMN1; SMN2 (0.55) | SMN1; SMN2HPNKDM4ARAB9ACACNA1H | |
| SCHEMBL30469092 | 0.83 | KDM4A (0.54) | SMN1; SMN2KDM4ARAB9ACACNA1HCACNA1B | |
| SCHEMBL25677972 | 0.83 | KDM4A (0.54) | SMN1; SMN2KDM4ARAB9ACACNA1HCACNA1B | |
| SCHEMBL19964549 | 0.81 | SMN1; SMN2 (0.51) | SMN1; SMN2HPNKDM4ARAB9ACACNA1H | |
| SCHEMBL23478663 | 0.79 | SMN1; SMN2 (0.48) | SMN1; SMN2KDM4ACACNA1HCACNA1BCACNA1C | |
| SCHEMBL30632885 | 0.79 | SMN1; SMN2 (0.48) | SMN1; SMN2KDM4ACACNA1HCACNA1BCACNA1C | |
| SCHEMBL30920730 | 0.79 | NQO2 (0.48) | SMN1; SMN2HPNKDM4ACACNA1HCACNA1B | |
| SCHEMBL30130020 | 0.78 | SMN1; SMN2 (0.48) | SMN1; SMN2HPNKDM4ARAB9ACACNA1H | |
| SCHEMBL30130041 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2HPNKDM4ARAB9ACACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018048930-A1 | LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA, INC. (US) | 2018-03-15 | — | — | WO | disclosed |